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Polycystic Ovary Syndrome (PCOS) Exam Study Questions with 100%v Correct Answers
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Polycystic Ovary Syndrome (PCOS) Exam Study Questions with 100%v Correct Answers
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Polycystic Ovary Syndrome (PCOS) ExamStudy Questions with 100%v Correct
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which problems associated with PCOS does metformin treat? 5
1. oligomenorrhea
2. hirsutism
3. infertility
4. obesity
5. prevention of type 2 DM
what is a TZD agent?
pioglitazone
what is the dose of pioglitazone?
45 mg daily
what is the MOA of pioglitazone?
improves insulin action in liver, skeletal muscle, and adipose tissue
pioglitazone is beneficial due to...
serum androgens
pioglitazone is a pregnancy category ___
C
pioglitazone may cause weight ___
gain
why is pioglitazone no longer recommended in PCOS?
risks greater than benefit
what is the GLP-1 agonist?
liraglutide (victoza/saxenda)
what is the dose of liraglutide?
, 0.6-3 mg daily
liraglutide causes ___ weight loss than metformin
greater
liraglutide is NOT to be used during ___
pregnancy
what is the concern with cycle control?
lack of withdrawal bleed may increase endometrial hyperplasia and increase risk of
endometrial cancer
what are pharmacological options to help with cycle control? 3
1. metformin
2. progestins
3. CHC
what is the rationale for hormonal contraception to help with cycle control? 3
1. suppresses free testosterone levels
2. minimizes menstrual irregularities
3. decrease adrenal androgen secretion
what can progestins induce?
withdrawal bleed if amenorrhea exists for 3 months or more
what are 2 continuous progestins?
1. IUDs
2. implant
what is the goal of intermittent progestins?
withdrawal bleeding every 1-3 weeks
what are the 2 intermittent progestins?
1. medroxyprogestone: 10 mg daily x 10-14 days
2. micronized progesterone: 400 mg daily x 10-14 days
what are progestins only used for?
cycle control and prevent endometrial hyperplasia
what do combination hormonal contraceptives contain? 2
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