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ONS/ONCC Chemotherapy Immunotherapy Certificate Exam Latest Questions And Answers (Verified Answers) $13.49   Add to cart

Exam (elaborations)

ONS/ONCC Chemotherapy Immunotherapy Certificate Exam Latest Questions And Answers (Verified Answers)

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ONS/ONCC Chemotherapy Immunotherapy Certificate Exam Latest Questions And Answers (Verified Answers)

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  • October 13, 2024
  • 31
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • ONS
  • ONS
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KenAli
ONS/ONCC Chemotherapy
Immunotherapy Certificate Exam Latest
2024-2025 Questions And Answers
(Verified Answers)


What 6 patient characteristics make CINV more likely? - ANSWER- 1. Younger than 50 years

2. Hx of low alcohol intake
3. Female gender
4. Hx of morning sickness during pregnancy
5. Prone to motion sickness
6. Previous chemotherapy

Types of CINV: - ANSWER- Acute
Delayed
Breakthrough
Anticipatory
Refractory

Define acute CINV - ANSWER- Occurring within 24 hours of chemotherapy

Define delayed CINV - ANSWER- Occurring from 24 hours to 5 days after treatment


Define breakthrough CINV - ANSWER- Occurring despite treatment

Define anticipatory CINV - ANSWER- Triggered by taste, odor, memories, visions, or anxiety
related to chemotherapy

Define refractory CINV - ANSWER- Occurring during subsequent cycles when treatment failed
in earlier cycles

Highly emetogenic chemo (HEC) causes CINV in more than ___% of patients - ANSWER- 90

Moderately emetogenic chemo (MEC) causes CINV in patients ___% to ___% of the time
- ANSWER- 30-90

Patients on low-potential emetogenic chemo develop CINV ___% to ___% of the time -
ANSWER- 10-30

,Minimal-risk emetogenic chemo causes CINV less than ___% of the time - ANSWER- 10

Common IV HEC drugs include: - ANSWER- Carmustine
Cisplatin

Cyclophosphamide
Dacarbazine
Mechlorethamine
Streptozosin

Common IV MEC drugs include: - ANSWER- Carboplatin

Cytarabine
Daunorubicin
Doxorubicin
Epirubicin
Idarubicin
Ifosfamide
Irinotecan

Oxaliplatin

Common low-potential IV emetogenic chemo drugs include: - ANSWER- 5-FU Cytarabine

Docetaxel
Etoposide
Gemcitabine
Methotrexate

Mitomycin C
Mitoxantrone
Paclitaxel
Pemetrexed

Common minimal-risk IV emetogenic chemo drugs include: - ANSWER-

Bleomycin
Bevacizumab
Bortezomib
Busulfan
Cetuximab
Fludarabine
Trastuzumab

Vinca alkaloids

,The 2 most important neurotransmitters involved in vomiting are: - ANSWER- 1. Serotonin

2. Substance P

Describe the peripheral pathway of CINV - ANSWER- Primarily occurs in the GI tract

Associated with acute CINV
Neurotransmitter --> serotonin

Describe the central pathway of CINV - ANSWER- Primarily occurs in the brain

Associated with delayed CINV
Neurotransmitter --> Substance P

Common serotonin 5-HT3 antagonists used for CINV: - ANSWER- Dolasetron
Granisetron
Ondansetron
Palonosetron

Common neurokinin-1 antagonists used for CINV: - ANSWER- Aprepitant Fosaprepitant

Common steroids used for CINV: - ANSWER- Dexamethasone

2 types of therapies that commonly have cutaneous reactions: - ANSWER- 1. EGFR inhibitor
therapies

2. Antimetabolites

Most-common cutaneous reaction seen with 5-FU and Capecitabine: - ANSWER-Palmar-plantar
erythrodysesthesia AKA hand-foot syndrome

Antimetabolites that commonly cause cutaneous reactions: - ANSWER- 5-FU Capecitabine
(Xeloda)

Define myelosuppression - ANSWER- Bone marrow activity is decreased, resulting in
fewer RBCs, WBCs and platelets

If severe: myeloablation

The most common dose-limiting toxicity of chemotherapy - ANSWER-Myelosuppression

Define nadir, and when does it occur? - ANSWER- The point at which blood cell counts are at
their lowest following a treatment cycle.

Typically occurs 7-10 days following cycle

, NCCN defines neutropenia as an ANC < _______/mm^3 - ANSWER- 500

Risk factors for developing neutropenia include: - ANSWER- > 65 years
old Hx of neutropenia with previous chemotherapy

Hx of chemotherapy or radiation treatment
Hematologic malignancy
Uncontrolled/advanced cancer
Lung cancer

Define neutropenic fever - ANSWER- Fever of 101 F or greater one time
OR

Fever of 100.4 F lasting one hour or longer

ANC calculation - ANSWER- (% polys + % bands) x

(WBC)/100 Normal WBC count - ANSWER- 4,500-10,000

Normal neutrophil count - ANSWER- 54%-62% of WBC

An ANC of less that _____ is considered a risk for infection - ANSWER- 1,000

Define thrombocytopenia - ANSWER- Low platelet count

Symptoms of thrombocytopenia - ANSWER- Petechiae or easily bruising Headaches

Hypotension and tachycardia
Prolonged bleeding (gums, menstruation)

Define anemia - ANSWER- Deficiency of RBC or hemoglobin in the blood

Symptoms of anemia - ANSWER- Dyspnea
Fatigue

Dizziness
Headaches

Acute diarrhea lasts: - ANSWER- 1-2 days and resolves on its own

Persistent diarrhea lasts: - ANSWER- 2-4 weeks

Chronic diarrhea lasts: - ANSWER- > 4 weeks

Common constipation-causing agents: - ANSWER- Vinca alkaloids (vincristine

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