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HDFN EXAM QUESTIONS AND 100% CORRECT ANSWERS
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HDFN EXAM QUESTIONS AND 100% CORRECT ANSWERSHDN
disorder in which the fetal and newborn cells are destroyed by maternal IgG antibodies
erythroblastosis fetalis
other term for hemolytic disease of the newborn
placenta
A structure that allows an embryo to be nourished with the mother's blood supply
barrier
the placenta acts as a natural ___ between fetal and maternal cells, reduces the chance
of Ab production
Fetomaternal hemorrhage
leakage of fetal cells into maternal circulation, typically occurring at the time of delivery
amniocentesis, abortion, cordocentesis, ectopic pregnancy, abdominal trauma
potential causes of fetomaternal hemorrhage (other than at delivery)
abruption of the placenta at the time of birth
most common cause of fetal maternal hemorrhage
IgG
class of antibody that can cross placental barrier
, fetal antigens
antibodies that cross placenta may bind to ____
liver, spleen
red cells are destroyed by macrophages in the fetal ___ and ___
subsequent pregnancy
the mother's pre-formed anti-Rh antibodies would attack the fetus' blood in a ___
indirect bilirubin
hemoglobin released from the damaged red cells is metabolized into ____
true
T/F: indirect bilirubin from fetal red cells is transported across the placenta for
excretion
maternal liver
indirect bilirubin from the fetal cells is conjugated by the___
anemic
the fetus becomes increasingly ___ as red cell destruction continues
enlargement
increased erythropoiesis in compensation of red cell destruction causes ___ of the fetal
liver and spleen
erythroblasts
these cells are released into fetal circulation in response to increased erythropoiesis
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