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Immunology PCB3233 Exam 1 UCF questions well answered

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Immunology PCB3233 Exam 1 UCF questions well answered

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  • October 9, 2024
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  • 2024/2025
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Immunology PCB3233 Exam 1 UCF

4 Human Pathogen Types - correct answer ✔✔viruses

parasites

fungi

bacteria



Extracellular infections accessible to - correct answer ✔✔soluble immune system molecules



Intracellular infections accessible to - correct answer ✔✔insoluble immune system molecules

in nucleus/cytosol = kill host cell

in vesicle = activate infected cell to increase antimicrobial activity



why do parasites infect other organisms - correct answer ✔✔complete life cycle



Compliment - correct answer ✔✔tags pathogens and extracellular molecules for destruction



MAC - correct answer ✔✔Membrane attack complex

C5-C9



Compliment Pathways (in chron. order) - correct answer ✔✔Alternative

Lectin

Classical



Compliment Fixation - correct answer ✔✔C3b contently binds to bacterium w/ thioester bond



Zymogen - correct answer ✔✔soluble proteases that circulate in inactive form

, 1st immune system component to be activated - correct answer ✔✔compliment



1st step in alternative pathway - correct answer ✔✔spontanious hydrolysis and activation of compliment
component C3



C3 Hydrolosis - correct answer ✔✔Where: Alternative pathway

spontaneous at low rate

no cleavage of C3

iC3 is product



Alternative C3 Convertaise - correct answer ✔✔Soluble

iC3Bb



Factor B - correct answer ✔✔binds to C3b



factors - correct answer ✔✔B = binds

D = cleaves

H = makes C3 susceptible to cleavage by I

I = cleaves C3b to iC3b

P = properdin, makes sure C3b not deposited on human cells, protects C3b from H



Opsonin - correct answer ✔✔facilitates phagocytosis

protein bound to pathogen surface



CR1 - correct answer ✔✔Compliment Receptor 1

binds to C3b on microbial surfaces->phagocytosis

protective role on human cells by disrupting C3 convertase

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