Pharmacology HESI Final Exam Prep/ Practice Questions with
Correct Verified Answers/ Latest Update 2024 – Rated A+
What is the pharmacokinetic process called when a drug is changed to a less active or inactive form by
enzymes?
a. distribution
b. absorption
c. metabolism
d. excretion - ANS - c.
Which routes are enteral? (Select all that apply)
a. subcutaneous
b. oral (PO)
c. sublingual
d. topical
e. buccal
f. intradermal - ANS - b,c,e
The _________ of a drug is the time it takes for the amount of drug in the body to decrease to one-half
of the peak level it previously achieved. - ANS - half-life
Which drugs treat absence seizures?
a. valproic acid
b. fluoxetine
c. baclofen
d. phenytoin - ANS - a.
, 2
A nursing student asks the instructor for tips on how to more easily learn pharmacology. The instructor
discusses the anticoagulant Heparin and states knowing Heparin and comparing other drugs to Heparin
will facilitate learning about the many anticoagulants. Which approach is the instructor using?
a. Generic name approach
b. Trade name approach
c. Mechanism of action approach
d. Drug classification approach - ANS - d.
Heparin is a generic name. Drugs are grouped together based on their similar properties. This is known
as a drug classification. Drugs can be classified by their structure (e.g., beta-adrenergic blockers) or by
their therapeutic use (e.g., antibiotics, antihypertensives, antidepressants). Within the broad
classification, each class may have subclasses; for example, penicillins are a subclass within the group of
antibiotics and beta-adrenergic blockers are a subclass within the group of antihypertensives.
When reviewing pharmacology terms for a group of newly graduated nurses, the nurse explains that a
drug's half-life is the time it takes for:
a. the drug to cause half of its therapeutic response.
b. one half of the original amount of a drug to reach the target cells.
c. one half of the original amount of a drug to be removed from the body.
d. one half of the original amount of a drug to be absorbed into the circulation. - ANS - c.
Another pharmacokinetic variable is the half-life of the drug. By definition, the half-life is the time
required for one-half (50%) of a given drug to be removed from the body. It is a measure of the rate at
which the drug is eliminated from the body.
What is the pharmacokinetic process called when a drug goes from the bloodstream to the site of
action?
a. distribution
b. metabolism
c. excretion
d. absorption - ANS - a.
, 3
With which drug is sleep walking an adverse effect?
a. valproic acid
b. lidocaine
c. baclofen
d. zolpidem - ANS - d.
amitriptyline is commonly used to treat neuropathic pain even though it is an antidepressant drug.
True or False - ANS - True
Which drug classifications require you to taper when discontinuing the drug? (Select all that apply)
a. Valproic acid
b. SSRIs
c. Tricyclic Antidepressants
d. Centrally acting muscle relaxants
e. Hydantoins
f. Benzodiazepines - ANS - c,d,e,f
____________ describes how the body affects drugs. - ANS - Pharmacokinetics
The therapeutic index describes the therapeutic result of a drug.
True or False - ANS - False
Which organs can have toxic effects from drugs? (Select all that apply)
a. heart
b. liver
c. brain
d. kidneys
e. lungs - ANS - All of the above
, 4
___________ describes how drugs affect the body. - ANS - Pharmacodynamics
What is the phenomenon called when drugs that are taken orally are delivered directly to the liver for
metabolism before distribution?
a. First-pass effect
b. Bioavailability
c. Biotransformation
d. Half-life - ANS - a.
The term used to describe when a drug is at it's highest level.
a. peak
b. toxicity
c. duration
d. onset - ANS - a.
The therapeutic effect is the intended effect of a drug.
True or False - ANS - True
A drug prototype represents a class of drugs
True or False - ANS - True
What are the rights of safe medication administration? (Select all that apply)
a. client
b. route
c. room
d. medication
e. dose
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