Question 1. The 43-year-old patient comes into the clinic with flu-like symptoms. The patient's onset of symptoms is less than 48 hours. The APN will prescribe oseltamivir and understands that the half-life is which of the following?
1.
20 to 24 hours
2.
6 to 10 hours
3.
2.5 to 5 hours
4.
1...
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PHARMACOTHERAPEUTICS
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FOR ADVANCED PRACTICE
NURSE PRESCRIBERS
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CHAPTER 23 & 24 WOO &
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,Question 1. The 43-year-old patient comes into the clinic with flu-like symptoms. The
patient's onset of symptoms is less than 48 hours. The APN will prescribe oseltamivir
and understands that the half-life is which of the following?
1.
20 to 24 hours
2.
6 to 10 hours
3.
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2.5 to 5 hours
4.
12 to 16 hours - ANS 2.
6 to 10 hours
Option 2:
Rationales
Option 1:
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The half-life for oseltamivir is 6 to 10 hours.
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The half-life for peramivir is 20 hours.
Option 3:
The half-life for zanamivir is 2.5 to 5.1 hours.
An APN is prescribing oseltamivir for the onset of flu-like symptoms to a 44-year-old
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patient. Which dosage is appropriate for this patient?
1.
75 mg PO bid for 5 days and start within 48 hours of symptoms
2.
75 mg PO bid for 4 days and start within 48 hours of symptoms
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3.
75 mg PO bid for 3 days and start within 48 hours of symptoms
4.
75 mg PO bid for 2 days and start within 48 hours of symptoms - ANS 1.
75 mg PO bid for 5 days and start within 48 hours of symptoms
Option 1:
75 mg PO bid for 5 days and start within 48 hours of symptoms is the correct dosage
and time frame.
, The APN diagnosed a 54-year-old patient with onychomycosis. Which medication
regimen is most appropriate for this patient?
1.
Itraconazole 100 mg PO once daily with meal for 12 consecutive weeks
2.
Itraconazole 200 mg PO once daily with meal for 12 consecutive weeks
3.
Terbinafine 200 mg PO once daily with meal for 12 consecutive weeks
4.
Terbinafine 100 mg PO once daily with meal for 12 consecutive weeks - ANS 2.
Itraconazole 200 mg PO once daily with meal for 12 consecutive weeks
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Option 2:
Itraconazole 200 mg PO once daily with meal for 12 consecutive weeks is the
appropriate medication and dosage.
Rationales
Option 1:
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Itraconazole 100 mg PO once daily is too low a dosage for this patient.
Option 3:
Terbinafine 250 mg PO once daily for 6 weeks may be prescribed for onychomycosis.
yc
Option 4:
Terbinafine 250 mg PO once daily for 6 weeks may be prescribed for onychomycosis.
When does the World Health Organization (WHO) endorse starting antiretroviral therapy
(ART) in a newly-diagnosed patient with HIV?
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1.
Within 7 days to the same day of newly-diagnosed HIV patient
2.
Within 20 days of newly-diagnosed HIV patient
3.
After the viral load numbers
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4.
Within 6 months of newly-diagnosed HIV patient - ANS 1.
Within 7 days to the same day of newly-diagnosed HIV patient
Option 1:
The WHO endorsed starting ART within 7 days of new diagnosis (WHO, 2017),
including same day, citing improved viral suppression.
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