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NURS 6521N Advanced Pharmacology Midterm Exam Questions and Complete Solutions Graded A+
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NURS 6521N Advanced Pharmacology Midterm Exam Questions and Complete Solutions Graded A+
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NURS 6521NAdvanced
Pharmacology
Midterm Exam
David Mungai [Date] [Course title]
,NURS 6521N Advanced Pharmacology Midterm Exam
Question 1
SGLT2 inhibitors may have a role in treating which of the following conditions?
A. Thyroid disorders
B. Pulmonary hypertension
C. Renal failure
D. Hepatic dysfunction
E. Cardiac arrhythmias
Correct Answer: C. Renal failure
Question 2
Which of the following phases is most concerned with drug absorption and metabolism?
A. Distribution phase
B. Pharmacokinetic phase
C. Storage phase
D. Pharmaceutical phase
E. Pharmacodynamic phase
Correct Answer: B. Pharmacokinetic phase
Question 3
Why is pyridostigmine useful in the symptomatic treatment of myasthenia gravis?
A. Pyridostigmine inhibits acetylcholinesterase, increasing acetylcholine availability.
B. Pyridostigmine increases the degradation of acetylcholine at the neuromuscular
junction.
C. Pyridostigmine acts as an immunosuppressant, reducing antibody production against
acetylcholine receptors.
D. Pyridostigmine blocks calcium channels in the presynaptic neuron.
E. Pyridostigmine directly stimulates acetylcholine receptors on the muscle cell surface.
,Correct Answer: A. Pyridostigmine inhibits acetylcholinesterase, increasing acetylcholine
availability.
Question 4
What is the first-pass effect?
A. Release of a drug's active ingredient from its formulation
B. Drug metabolism in the liver before reaching systemic circulation
C. Immediate drug effect upon first administration
D. Initial drug distribution and plasma protein binding
E. Complete drug elimination after first use
Correct Answer: B. Drug metabolism in the liver before reaching systemic circulation
Question 5
Intravenous heparin would be best used in which of the following situations?
A. In a patient with stable angina
B. In a patient with a recent epidural hemorrhage
C. In a patient with carotid artery stenosis
D. In a patient with atrial fibrillation
E. In a patient with myocardial infarction which was treated by coronary angioplasty
Correct Answer: E. In a patient with myocardial infarction which was treated by coronary
angioplasty
Question 6
What are the two major classes of medications used to manage angina pectoris?
A. Vasoconstrictors and cardiac depressants
B. Vasodilators and cardiac stimulants
C. Inotropes and vasoconstrictors
D. Vasodilators and cardiac depressants
E. Vasoconstrictors and cardiac stimulants
Correct Answer: D. Vasodilators and cardiac depressants
, Question 7
What most accurately describes the mechanism of action of tiagabine on gamma-aminobutyric
acid (GABA)?
A. GABA-B receptor antagonist
B. GABA-B receptor agonist
C. Inhibition of GAT-1
D. GABA-A receptor antagonist
E. GABA-A receptor agonist
Correct Answer: C. Inhibition of GAT-1
Question 8
Which medication is a muscarinic agent that prevents bronchoconstriction caused by vagal
discharge and is often used in both children and adults?
A. Ipratropium (Atrovent)
B. Salmeterol (Serevent)
C. Formoterol (Foradil)
D. Albuterol (Ventolin)
E. Theophylline (Theo-24)
Correct Answer: A. Ipratropium (Atrovent)
Question 9
Why is pyridostigmine taken multiple times a day for the management of myasthenia gravis?
A. It is rapidly degraded.
B. Patients rapidly develop tolerance to its effects.
C. It requires a high concentration in order to be effective.
D. It interacts with other medications, reducing its effectiveness over time.
E. It has a slow onset of action.
Correct Answer: A. It is rapidly degraded.
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