MCIM 321 Actual Questions and
CORRECT Answers
Allelic Exclusion - CORRECT ANSWER- Process by which only one allele of a gene is
expressed and the other silenced
Idiotype - CORRECT ANSWER- is a shared characteristic between a group of
immunoglobulin or T cell receptor (TCR) molecules based u...
MCIM 321 Actual Questions and
CORRECT Answers
Allelic Exclusion - CORRECT ANSWER✔✔- Process by which only one allele of a gene is
expressed and the other silenced
Idiotype - CORRECT ANSWER✔✔- is a shared characteristic between a group of
immunoglobulin or T cell receptor (TCR) molecules based upon the antigen binding
specificity and therefore structure of their variable region.
Allotype - CORRECT ANSWER✔✔- the allele of the antibody chains found in the
individual.
Opsonin - CORRECT ANSWER✔✔- antibody that specifically enhance phagocytosis or
opsoization of the antigen.
Humoral Immunity - CORRECT ANSWER✔✔- soluble antibody present in immune serum.
Has characteristic that its effect can be transferred from immune to non immune animals by
transfering serum.
Antibodies - CORRECT ANSWER✔✔- Bind to antigens
Prophylactic immunization - CORRECT ANSWER✔✔- The artificial establishment of
specific immunity
Immune characteristics - CORRECT ANSWER✔✔- Specificity and adaptibility
,Induction of antibody - CORRECT ANSWER✔✔- Process by which antigen interacts with
the cells of the immune system to result in the production of antibody
Unispecific cells - CORRECT ANSWER✔✔- Cells that are predestined to make antibody of
only one specificity
Inducible - CORRECT ANSWER✔✔- Immune system is not constitutive but is
__________. The latent period, during which there is little or no immunity, is considerably
shorter upon secondary exposure.
Innate defense mechanisms - CORRECT ANSWER✔✔- Due to molecules that are usually
constituitivly present in amounts effective against a typical exposure to a pathogen, or
mediated by cells that are sufficiently frequent to be effective against a pathogen even in an
animal that has not been prrreviously exposed
Macrophages - CORRECT ANSWER✔✔- Phagocytes such as __________, are often the
first cells to engage a foreign invader, it is understandable that phagocytes posses a wide
variety of biochemical mechanisms to attach such invaders.
IFNy - CORRECT ANSWER✔✔- ____ activates by binding to IFNy receptors on the
macrophage surface, the synthesis of reactive nitrous oxide and the production of free and
reactive oxygen species that can damage the invaders
Phagocytosis - CORRECT ANSWER✔✔- _________ of a pathogen is enhanced when
antibody binds to the pathogen. Thus the antibody produced following bacterial infection can
bind to phagocytes and aid the injestion of bacteria.,
IFN-a - CORRECT ANSWER✔✔- produced by virally infected lymphocytes
IFN-b - CORRECT ANSWER✔✔- Produced by virally infected fibroblasts
IFN-y - CORRECT ANSWER✔✔- - Secreted by some lymphocytes when interacting with
antigen
- Not infected by virus but rather secretion helps local cell populus
Instructive theory - CORRECT ANSWER✔✔- Antigen acts as a template. Antigen is
required to instruct the immune system to make antibody complementary to the antigen
Selective theory - CORRECT ANSWER✔✔- Interaction of antigen with receptor was
envisaged to select for the receptor for further synthesis and secretion
Epitopes - CORRECT ANSWER✔✔- Surface groupings, able to be recognized and bound
by antibody are termed
Autoreactivity - CORRECT ANSWER✔✔- shows the individual has the genetic capacity to
make antibody against self antigen.
IFN's - CORRECT ANSWER✔✔- They increase the phagocytic and anti microbial activity
of macrophages and the cytotoxicity of NK cells.
IL1 - CORRECT ANSWER✔✔- Leukocyte Communication molecule
acts on temperature control center of hypothalamus to induce fever in response to endotoxin
such as the LPS.
PAMP's - CORRECT ANSWER✔✔- Molecular patterns present among groups of pathogens
that are not on self antigens
Acute Imflammation - CORRECT ANSWER✔✔- Due to accumulation of fluids and
infiltration by polymorphonuclear neutrophils.
Means of bringing cells and proteins to a site in defense against trauma.
Mast Cells - CORRECT ANSWER✔✔- These cells are strategically located in solid tissue
adjacent to small arteries and contain prominent granules. The content of the granules are
released upon mast cell activation by the process of degranulation, and they contain a host of
mediators. Histamine is a prominent mediator.
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