Exam (elaborations)
Breast Pathoma: Questions With Complete Solutions
- Course
- Institution
Breast Pathoma: Questions With Complete Solutions
[Show more]
Content preview
Breast Pathoma: Questions With Complete SolutionsMilk line Right Ans - Breast tissue can develop anywhere from the axilla to
the vulva
Lobules and ducts are lined by two layers of epithelium Right Ans - luminal
cells - milk production
myoepithelial cells - contractile function
Is galactorrhea a symptom of Breast cancer? Right Ans - No
caused by nipple stimulation, prolactinoma and dopamine anatagonists
Acute mastitis in breast feeding women is usually caused by ________
Tx? Right Ans - *Staph aureus* invasion of fissures that develop during
*breast feeding*
Tx: *dicloxacillin*
70%-80% of cancers that are detected on mammogram are ______ Right Ans
- invasive
Risk factors for breast cancer? Right Ans - -benign breast disease
-estrogen exposure
-radiation (hodgkins tx)
-Obesity & alcohol
Poorly differentiated medullary cancers, ER- HER2- basal genetic
classification.
, genetic marker? Right Ans - BRCA1
more Poorly differentiated, more likely ER+, HER-
Luminal genetic classification
What gene? Right Ans - BRCA2
Chromosome 1q, overexpression of homeobox transcription factor HOXB13
Right Ans - Phyllodes tumor
Malignant clonal proliferation limited to ducts and lobules (has not broken
through the basement membrane)
• Stage 0 breast cancer
• Myoepithelial cells preserved Right Ans - DCIS
Atypical apocrine adenosis thought to be precursor, amplification of TP53 on
chrom 17q, ER + or ER- Right Ans - HER2 positive pathway
Most common mutation in sporadic cancer Right Ans - TP53
Which three are the most likely fibrocystic changes to cause cancer? Right
Ans - Atypical ductal > lobular
Atypical ductal and lobular hyperplasias have what change in genetic
material? Right Ans - loss of 16q or gain of 17p
Atypical lobular hyperplasia has a loss of E-cadherin
erythematous breast w/ purulent nipple discharge Right Ans - acute
mastitis
Smoker with subareolar mass and nipple retraction.
Location? Right Ans - periductal mastitis
Squamous metaplasia of lactiferous ducts
Periareolar mass w/ green-brown (or *thick white*) nipple discharge.
age group? disease? MOA? Right Ans - -Mammary Duct Ectasia
-Multiparous postmenopausal women
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller LeCrae. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $9.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
77254 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now