Summary
Summary LEUKEMIA -- HEMA 2
- Course
- Institution
- Book
Concise, but well-explained. Seems like reading a book, but with bite-sized information
[Show more]
Connected book
Book Title:
Author(s):
- Edition:
- ISBN:
- Edition:
More summaries for
-
ANEMIAS - HEMA 2
-
Test Bank for Rodak’s Hematology 6th Edition Walenga | Chapter 1 - 43| Updated Guide 2022
-
Test Bank for Rodaks Hematology 5th Edition by Keohane
Seller
Follow
nykkareyes
Content preview
Lymphocytes............................................................................................................................................ 2Cytochemical Stains................................................................................................................................. 3
Enzymatic.......................................................................................................................................................... 3
LAP Score.......................................................................................................................................................... 4
Nonenzymatic................................................................................................................................................... 5
Neoplasms...............................................................................................................................................................6
Leukemia........................................................................................................................................................7
FAB Classification: French-American-British Classification....................................................................... 7
WHO Classification................................................................................................................................................. 8
Acute Myeloproliferative Leukemia (AML)............................................................................................................ 8
Myeloproliferative Neoplasms............................................................................................................................. 11
Chronic Myeloid Leukemia (CML)..................................................................................................................11
Polycythemia Vera (PV)...........................................................................................................................11
Acute Lymphoid Leukemia (ALL).................................................................................................................. 12
FAB Classification of ALL........................................................................................................................ 12
Chronic Lymphoproliferative Leukemic Disorders (CLLD)............................................................................ 13
Chronic Lymphocytic Leukemia (CLL).....................................................................................................13
Hairy Cell Leukemia (HCL)......................................................................................................................13
Lymphomas and Other Leukocyte Disorders.................................................................................................14
Hodgkin's Lymphoma and Non-Hodgkin’s Lymphoma..................................................................................14
Mycosis Fungoides or Sezary Syndrome......................................................................................................14
Mantle Cell Lymphoma (MCL).......................................................................................................................14
Burkitt Lymphoma..........................................................................................................................................14
Multiple Myeloma (MM)................................................................................................................................. 14
Waldenstrom’s Macroglobulinemia (WM)......................................................................................................14
Heavy Chain Disease (HCD).........................................................................................................................14
, Lymphocytes
Leuko - white, cyte - cell – white blood cells (WBC) circulate and function as our body’s main line of defense. WBCs
protect the body against bacteria, viruses, and other foreign bodies. WBCs arise from the Common Myeloid Progenitor
(CMP) or CFU-GEMM (Colony forming unit – granulocyte, erythrocyte, monocyte, and megakaryocyte) progenitor cell. As
this cell line matures, multilineage colonies form: CFU-GM (granulocyte and macrophage), CFE-Meg (megakaryocyte), and
CFU-E (erythroblast). WBCs are generally classified according to:
- Granules (granulocytic or non granulocytic)
- Nuclear segmentation
- Function as either phagocytic or immunologic
The granulocytes – neutrophils, eosinophils, and basophils – contain distinct granules in their cytoplasm.
However, non granulocytes – monocytes and macrophages – lack prominent granules. This classification is mainly based
on their reaction to Romanowsky or Wright stains.
Granulocyte Characteristic Stain of their Rational Picture
granules
Eosinophil Band shaped or Bright orange-pink Affinity for eosin
segmented into only 2 (acidic component of
segments the stain)
Neutrophil Lobes (2-4) are Light pinkish-purple or Remains neutral
connected by a pink tan
threadlike filament
Basophil Round, indented, band Dark purple-blue Affinity for methylene
shaped blue
(basic component of
Usually difficult to see the stain)
because of overlying
granules
Nuclear segmentation is another
classification of WBCs. Polymorphonuclear
(PMN) cells – neutrophils, eosinophils, and
basophils – have a multilobed or segmented
nucleus. On the other hand, mononuclear cells
– monocytes (see Figure 1) and lymphocytes
(see Figure 2) have a single mass of nucleus.
Lastly, phagocytic cells – neutrophils,
eosinophils, basophils, monocytes – engulf and
destroy foreign invaders, while lymphocytes,
which are immunologic cells, primarily function
in antibody production.
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller nykkareyes. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $7.49. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
78252 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now