How are androgens and estrogens involved in bone growth?
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Increase protein matrix and cells that create bone to increase bone
strength; leads to closure of growth plates
What are the main drivers behind PTH and calcitonin?
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osteoclasts
What is unique about the thyroid?
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Only endocrine organ in the body to store hormone product OUTSIDE of
the cell
What transports thyroid hormone in the blood? Why is this necessary?
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TBG because most blood is water, so thyroid hormone must be attached
to a protein that dissolves well in blood
What are actions of thyroid hormone? (5)
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-increases BMR
-stimulates synthesis of the Na/K ATPase
-regulates metabolism
-up-regulates beta receptors for catecholamines
-permissive with most aspect of growth
, What is peripheral conversion?
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Every cell has the capability to convert T4 to T3
Where do parafollicular (c) cells sit?
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outside of follicular cells
What is hypothyroidism?
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Failure of the thyroid gland to produce thyroid hormones
Where is the thyroid found?
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In front of trachea, below thyroid cartilage (part of larynx)
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