UC NURS8022 Endocrine Patho Exam Questions And Correct Solutions New Update (Verified Pass)
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Course
NURS 8022
Institution
NURS 8022
UC NURS8022 Endocrine Patho Exam Questions And Correct Solutions New Update (Verified Pass)
Mechanism of hormonal regulation - Answer -*Failure of feedback system
*Dysfunction of endocrine gland- excess or inadequate production
*Altered hormone- inactivation or degradation
*Ectopic hormone re...
UC NURS8022 Endocrine Patho Exam
Questions And Correct Solutions
New Update (Verified Pass)
Mechanism of hormonal regulation - Answer -*Failure of feedback system
*Dysfunction of endocrine gland- excess or inadequate production
*Altered hormone- inactivation or degradation
*Ectopic hormone release from non-endocrine sites or autonomous production
*Failure of target cell response to hormone- receptor or intracellular disorder
*SIADH pathology - Answer -ADH (anti-diuretic hormone) level abnormally high
*Most common cause of SIADH - Answer -Ectopic secretion of ADH (also after surgery
or some cancers)
*SIADH: Water retention - Answer -Action of ADH on renal collecting ducts increases
their permeability to water- increases water reabsorption by kidneys
*SIADH diagnosis criteria - Answer -Normal renal, adrenal, and thyroid function must
exist
*SIADH Nephrogenic form - Answer -Excess free water
*SIADH Genetic form - Answer -Mutation in arginine vasopressin AVP gene
*SIADH characterized by - Answer -Euvolemic hypotonic (dilutional) hyponatremia
*SIADH manifestations - Answer -*Total body water: increased
*Total body serum: unchanged
*Extracellular fluid: increased
*Edema: absent
*SIADH symtoms - Answer -*Hyponatremia
*Serum hypoosmolality (<280 mOsm)
*Urine hypersolmolality
*Euvolemia (no sign of volume change)
*Weight gain
*Headache, N/V, confusion
*Sever hyponatremia
*CAN LEAD TO COMA, CONVULSIONS, DEATH
*(ADH insufficiency) Neurogenic (central) - Answer -Deficiency in brain, insufficient
amount of ADH produced
, *(ADH insufficiency) Nephrogenic (renal) - Answer -Kidneys don't react to ADH.
Insensitivity of renal collecting tubules to ADH
*(ADH insufficiency) Nephrogenic (renal) Patho - Answer -*Genetic: X-linked
*Acquired: Meds, second messenger defect, CKD, hypercalcemia, hypokalemia, cancer
*(ADH insufficiency) Dipsogenic/Psychogenic - Answer -Excessive fluid intake. Lowers
plasma osmolarity to point that it falls below threshold for ADH secretion
ADH insufficiency manifestations - Answer -*Inability of kidneys to decrease
permeability to water
*Excretion of large volumes of dilute urine
*Increase in plasma osmolality (>300 mOsm)
*Hypopituitarism patho - Answer -*Absence of selective pituitary hormones
*Complete failure of all pituitary hormone functions (panhypopituitarism)
Pituitary is _____ and venerable to _____ and _____ - Answer -Vascular, ischemia,
infarction
*(Hormones affected by Hypopituitarism) TSH deficiency - Answer -Altered metabolism
*(Hormones affected by Hypopituitarism) FSH and LH deficiency - Answer -Lack of
secondary sex characteristics
*(Hormones affected by Hypopituitarism) GH deficiency - Answer -Lack of growth in
children
*Hyperpituitarism patho - Answer -Commonly from benign, slow-growing, pituitary
adenoma
*Hyperpituitarism manifestations - Answer -*Headache and fatigue
*Visual changes (close to optic chiasm)
*CN palsies
*Hypersecretion of pituitary from tumor
*Hyposecretion of anterior pituitary hormones (Hypocortisol and Hypotyroid)
*Hyperpituitarism Giantism - Answer -GH hypersecretion in children and adolescents-
affects long bone growth
*Hyperpituitarism Acromegaly - Answer -GH hypersecretion in adulthood- caused by
slowly progressive pituitary adenoma
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