1/2 life (T 1/2) Correct Answer Time it takes to get rid of half
of the drug; gives us good time to administer rest of the dose and
when we can expect to see side effects
4 phases of clinical trials Correct Answer 1. small group to
evaluate safety (safe dose range and identify side effects)
2. larger group to see if it's effective and safe
3. large group to confirm effectiveness, monitor side effects,
compare with other treatments and collect more info
4. studies done after drug has been marketed to get information
on different populations and assess side effects with long-term
use.
6 rights of administration Correct Answer 1. Right patient
2. Right drug
3. Right dose
4. Right route
5. Right time and frequency
6. Right documentation
a nurse assesses an older patient taking a drug meant to lower
BP for what adverse effect Correct Answer postural
hypotension
a nurse assesses an older patient taking antidiabetic drugs for
what adverse effect Correct Answer altered glycemic response
,A reduction in _______ and _____ alters the volume of
distribution of drugs in the older adult Correct Answer lean
body mass, total body water
a reduction in which physiological characteristic in the older
adult reduces the hepatic clearance of drugs Correct Answer
liver size and blood flow
Acidic drugs bind to Correct Answer albumin/lipoproteins
additive Correct Answer Sum of effects of two drugs
adverse effects of polypharmacy Correct Answer falls,
confusion, nonadherence
adverse reaction Correct Answer more severe than side effects,
always undesirable
agonist Correct Answer Activate receptors to produce a desired
response
an older adult with hypertension has been prescribed a diuretic.
what assessment finding would prompt the nurse to hold the
medication and contact the health care provider Correct Answer
if the patient's heart rhythm was irregular
an older patient states that they know the medication is due to be
taken before breakfast but that they always forget. What
intervention by the nurse is appropriate Correct Answer use
memory aids such as a pill organizer or alarm
, Antagonist Correct Answer Prevent receptor activation (blocks
the response); one drug blocks/reduces effects of other drug
Beneficence Correct Answer protecting the client from harm
competencies Correct Answer patient-family-centered care,
collaboration and teamwork, evidence-based practice, quality
improvement, safety, and informatics
Comprehensive Drug Abuse Prevention and Control Act of 1970
Correct Answer promoted drug education, strengthened
enforcement authority, established treatment facilities, and
designed categories for controlled substances.
-instituted controlled substances categories
culture of safety Correct Answer a blame free environment in
which staff can practice & openly discuss potential errors or
near-misses as well as actual errors
Dietary Supplement Health and Education Act Correct Answer
labeling requirements for dietary supplements
drug Correct Answer Chemical that affects physiologic process
of a living organism
Drug Abuse Control Amendments Correct Answer gave FDA
more control over
-amphetamines
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