NR-565 Advanced Pharmacology
Fundamentals Final Exam Study Guide |
100% Pass| Graded A +
Administrator [Date] [Course title]
,NR-565 Advanced Pharmacology Fundamentals Final Exam Study Guide
| 100% Pass| Graded A +
1. WEEK 5 ...
2. Thyroid 5.
o Diagnosis
& Evaluation
What labs are
used to diag-
nose?
3. Thyroid
o Diagnosis
& Evaluation
Timeframe for
re-check of
labs after
starting
levothyroxine?
4. Thyroid
o Diagnosis
& Evaluation
Signs and symp-
toms of
hypothy-
roidism?
, NR-565 Advanced Pharmacology Fundamentals Final Exam Study Guide
| 100% Pass| Graded A +
-TSH - used serum TSH is stabilized
primarily for
screening and
diagnosing hy-
pothyroid and for
monitoring
replacement
therapy in hy- Hypothyroidism: Depend on severity.
pothyroid o Mild: subtle and may go unrecognized
patients o Moderate to severe:
-Face is pale, puffy, and expressionless.
-T4 - Used to -Skin cold and dry.
monitor thyroid -Hair is brittle and hair loss occurs.
hormone -Slowed Heart rate.
replacement ther- -Patient may complain of lethargy, fatigue, and
apy and to screen -Temperature is lowered & intolerant to cold.
for thyroid -Thyroid Enlargement may occur if reduced
dysfunction levels of T3 and T4
Mentation may be impaired.
-T3 - Useful in the
diagnosis of
hyperthyroidism;
can also be used
to monitor
hormone
replacement
therapy
-TSH low
-T4 normal
-T3 is high =
hyperthyroidism
Recheck TSH 6-8
weeks after
initiating therapy
and after any
dosage change;
Check TSH at least
once a year after
, NR-565 Advanced Pharmacology Fundamentals Final Exam Study Guide
| 100% Pass| Graded A +
Thyroid o Elevated Heart rate and strong, and
o Diagnosis dysrhythmias and angina may develop
& Evaluation o The CNS is stimulated, resulting is nervousness,
insom- nia, rapid thought flow, and rapid speech,
Signs and symp- hyperreflexia, tremors
toms of hyper- o Skeletal muscles may weaken and atrophy
thyroidism? o Metabolic rate is raised, resulting in health and
skin that is warm and moist
o Feeling Hot + Heat intolerance
o Appetit is increased but fails to match
metabolic rate resulting in weight loss
o All of these signs are referred to as thyrotoxicosis
o Also usually present with exophthalmos -
bulging of the eyes
6. Thyroid Characterized by profound hyperthermia (105
o Treatment degrees F or higher), severe tachycardia,
restlessness, agitation, and tremor.
Treatment of Unconsciousness, coma, hypotension, and heart
thy- roid storm? failure may ensure.
These symptoms are produced by excessive
levels of thyroid hormone
Thyroid crisis can be life threatening and
requires imme- diate treatment.
o High doses of potassium iodide or strong iodine
solution are given to suppress thyroid hormone
release.
o Methimazole is given to suppress thyroid
hormone syn- thesis
o A beta blocker is given to reduce heart rate
o Additional measures include sedation, cooling,
and giv- ing
glucocorticoids and IVF
7. Thyroid
o Treatment Can result in permanent neuropsychological
deficits in the child - decrease child's IQ
Result of not The effect of hypothyroidism is limited largely
treating hypothy- to the first trimester, a time during which the
fetus is unable to produce thyroid hormone of
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