A patient administered aminoglycoside
(gentamyacin) complains of sudden hearing loss.
What should the nurse practitioner do? -
....ANSWER...Stop the medication as they patient is
experiencing ototoxicity
Which medications interact with linezolid? -
....ANSWER...MAOIs, SSRIs, Tyramine rich foods
(Aged cheese, wine, alcohol). Also avoid pethidine or
meperidone due to risk of serotonin syndrome
What is the treatment with doxycycline for treatment
of lyme disease? - ....ANSWER...100 mg PO BID x 21
days
,What are the main side effects of doxycycline? -
....ANSWER...Anorexia, nausea, vomiting, diarrhea,
dizziness, vertigo, photosensitivity
Differentiate between oral and parenteral
vancomyacin? - ....ANSWER...IV for systemic therapy
as it does not absorb via intestines. Oral
vancomyacin is only given for C. Diff infection to
reach site
What is the mechanism of action of azithromyacin? -
....ANSWER...Macrolides bind to P site of 50S
ribosome subunit and may inhibit RNA dependent
protein synthesis by preventing peptidyal-tRNA from
ribosomes.
What are the side effects of azithromyacin? -
....ANSWER...GI associated - Nausea, vomitting, abd
,pain, cramping, diarrhea. Can also cause hepatitis
and hepatic failure
What vitamin will decrease peripheral neuropathy? -
....ANSWER...Vitamin B6 - Pyroxodine
What lab values should be assessed when
administering valacyclovir? - ....ANSWER...BUN and
Creatinine
When should oseltamivir phosphate be prescribed? -
....ANSWER...First 48 hours of symptoms
What is rifampin prescribed for? - ....ANSWER...TB,
Leprosy, and Legionella as well as HIB and
Meningitis
What are the adverse effects of Isoniazid (INH)? -
....ANSWER...Used for TB. Elevated LFTs and
inflammation causing peripheral neuropathy and
liver inflammation
When is prophylactic oseltamivir recommended? -
....ANSWER...Not used regularly but can be used for
, outbreaks and long term care homes as well as
immunosuppressed patients
When prescribing ketoconazole, how should it be
administered? - ....ANSWER...Antifungal used orally
or topically. Used for dandruff and tinea
What is hypochlorhydria? - ....ANSWER...decrease in
production of gastric secretions - hydrochloic acid
What lab values should be monitored when
administering antifungal agents? - ....ANSWER...LFTs
Which antihelmintic is used to treat parasitic
worms? - ....ANSWER...Mebendazole and Ivermectin
- Intestinal
Albenderzole, Mebendazole, or Ivermectin - Tissue
What antifungal medications can be used topically to
treat fungal infections? - ....ANSWER...Clotrimazole
What are the main side effects of ethambutol? -
....ANSWER...Optic neurotis, red-green
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