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NURB 3150 ANTIEPILEPTICS EXAM LATEST UPDATE
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NURB 3150 ANTIEPILEPTICS EXAM LATEST UPDATE ...
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NURB 3150 ANTIEPILEPTICSEXAM LATEST UPDATE
antiepileptic drugs - Answer Benzos
Hydantoins
Barbiturates
Iminostilbenes
Succinimides
Gabapentin
Anticonvulsants
withdrawal seizures - Answer You cannot discontinue antiepileptics abruptly because it
causes ______________ _____________.
#1 reason for exacerbations is ineffective management of medications
antiepileptics - Answer monitor for emergence or worsening depression, suicidial
thoughts/behavior, or any changes in mood or behavior
antiepileptics - Answer -Increase thereshold of activity in motor cortex
-Limit the spread of seizure discharge from origin
-Decrease the speed of nerve impulses
Benzos - Answer Diazepam
Lorazepam
Midazolam
Alprazolam
Benzos - Answer FIRST LINE DRUGS → Status epilepticus, anxiety, ETOH withdrawal
Benzos - Answer Increase inhibitory effects of GABA in CNS
Benzos - Answer FLUMAZENIL= ANTIDOTE
Benzos - Answer Careful for resp depression in combo w/ opioids
Status epilepticus - Answer continuous seizure activity
, Hydantoins - Answer Phenytoin
Fosphenytoin
Hydantoins - Answer Tx all seizures EXCEPT ABSENCE SEIZURES (makes worse)
Hydantoins - Answer Contra: Bradycardia, AV blocks
Hydantoins - Answer RASH
Long term- gingival hyperplasia, hirsutism, osteoporosis
Toxic levels- Ataxia, nystagmus, diplopia
Hydantoins - Answer Concern with low albumin levels! (3.5-5.5)
Hydantoins - Answer No warfarin, oral contraceptives or IV dextrose solutions NS only!
(flush before and after)
PO give with meals
10-20 mg/L - Answer Therapeutic Serum Level of Hydantoins
50 mg/min - Answer Hydantoins--> SLOW IVP no more than ______________
if given faster can cause CV collapse (severe hypotension, life threatening
dysrhythmias)
MONITOR VS during infusion
Fosphenytoin - Answer rapidly converted to Phenytoin in body
1/2 life = 15 min
can give IV and IM
can give at faster rate and compatible with D5W and NS
check VS for 2 hours after infusion
Barbiturates - Answer Phenobarbital
Barbiturates - Answer Not effective against absence seizures
Tx/prevent febrile seizures in infants/young kids
Barbiturates - Answer *Steven-Johnson syndrome*
CNS effects IV- *Resp. depression*/apnea
Toxic- ataxia, nystagmus, pinpoint pupils, coma
Barbiturates - Answer Contra: Resp disease, CNS depressants/ETOH
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