AQA GCSE 8464 B 2F QP COMBINED SCIENCE TRILOGY JUNE
2024
2024
, Please write clearly in block capitals.
Centre Candidate
number number
Surname
Forename(s)
Candidate ure
signat
GCSE
F
COMBINED SCIENCE: TRILOGY
Foundation
Friday 7 June 2024 Afternoon Time allowed: 1 hour 15 minutes
Materials
For Examiner’s Use
For this paper you must have:
a ruler Questio Mark
a scientific calculator. n
1
Instructions 2
Use black ink or black ball-point pen.
3
Pencil should only be used for drawing.
Fill in the boxes at the top of this page. 4
Answer all questions in the spaces provided. 5
If you need extra space for your answer(s), use the lined pages at the end of this 6
book. Write the question number against your answer(s).
Do all rough work in this book. Cross through any work you do not want to be TOTAL
marked.
In all calculations, show clearly how you work out your answer.
Information
The maximum mark for this paper is 70.
The marks for questions are shown in brackets.
You are expected to use a calculator where appropriate.
You are reminded of the need for good English and clear presentation in your answers.
*Jun24 464 2F01*
IB/M/Jun24/G4005/E8
8464/B/2F
, 2
Do not write
outside the
Cystic
0 fibrosis
1 is a genetic disorder. box
0 1 .1 Cystic fibrosis affects the movement of substances into and out of cells.
Which part of a cell controls the movement of substances into and out of the cell?
[1 mark]
Tick () one box.
Cell membrane
Cytoplasm
Mitochondria
Cystic fibrosis is caused by a recessive allele, b.
0 1 .2 What name is given to the allele B?
[1 mark]
Tick () one box.
DNA
Dominant
Gene
0 1 .3 Which term describes the genotype Bb?
[1 mark]
Tick () one box.
Chromosome
Heterozygous
Phenotype
*02
IB/M/Jun24/8464/
* B/2F
, 3
Do not write
outside the
0 1 .4 Two people plan to have a child. box
Both people have the genotype Bb.
Complete Figure 1 to show the possible genotypes of the child.
[3 marks]
Figure 1
0 1 .5 What is the chance that a child of these parents will have cystic fibrosis?
Use Figure 1. Tick
[1 mark]
() one box.
0% 25% 50% 75%
Question 1 continues on the next page
Turn over ►
*03
IB/M/Jun24/8464/
* B/2F
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