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NURO 670 Midterm - Renal-LFTs-Pancreas Exam Study Guide $9.99   Add to cart

Exam (elaborations)

NURO 670 Midterm - Renal-LFTs-Pancreas Exam Study Guide

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NURO 670 Midterm - Renal-LFTs-Pancreas Exam Study Guide ...

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  • September 19, 2024
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  • Exam (elaborations)
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  • azotemia
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NURO 670 Midterm -
Renal-LFTs-Pancreas Exam
Study Guide

BUN- Answer blood urea nitrogen; 5-25 normal

byprod of nitrogenous metabolism

excreted by kidneys

azotemia- Answer increased nitrogenous waste

uremia- Answer toxic condition, kidneys unable to excrete urea + other toxins

what causes increased BUN?- Answer -increased protein catabolism (septic, trauma)

-decreased renal perfusion (prerenal)

-intrarenal dysfunction (nephrotic syndrome, meds)

-obstructive uropathy

-any pre/intra renal failure will produce DECREASE in GFR and DECREASE urea
excretion

**GI bleed? digestion of RBCs

increased BUN s/s- Answer fatigue, wkness, seizures, lethargy, confusion, pruritis

*uremic bleed? PLT dysfunctions

increased BUN tx- Answer determine + fix underlying cause.

-prerenal - improve perfusion

-intra - stop toxins/meds, tx cause

basically water the kidneys and dialyze

Creatinine definition- Answer byprod of creatinine phosphate metabolism

normal 0.6-1.5

male>female d/t muscle mass

, completely excreted by kidney - reflects GFR

what causes elevation in Cr?- Answer renal shit.

muscle wasting, HF, shock, rhabdo

BUN:Cr ratio- Answer 10:1 - intrarenal pathology

20:1 - prerenal pathology

Creatinine clearance- Answer indicative of GFR

compares amt of creatinine in urine to amt in blood/serum

male 125/min ; female 105/min

CrCl cockcroft gault equation- Answer (140-age) x IBW/72 x Cr(mg/dL) [women =
multiple by 0.85]

ideal body wt- Answer male = 50kg + (inch >60 x 2.3)

female = 45.5kg + (inch >60 x 2.3)

relationship of Cr vs GFR- Answer **doubling Cr = GFR decrease 50

Cr 1 = GFR 100

Cr 2 = 50

4 = 25

what labs can be used to determine renal function?- Answer urine Na - 20-40

FeNa - 1-2%

urine plasma/Cr ratio - 20-40

renal failure index - 1-2

urine plasma/osm ratio - >1

(normals are listed)

prerenal problem = what labs?- Answer urine Na <30

FeNa <1%

urine plasma/cr ratio >30

RFI <1

urine plasma/osm ratio >1.4

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