JACI PRIMER EXAM ACTUAL EXAM 120 QUESTIONS AND CORRECT DETAILED ANSWERS WITH RATIONALES (100% VERIFIED ANSWERS) |ALREADY GRADED
1 view 0 purchase
Course
2024/2025
Institution
2024/2025
JACI PRIMER EXAM ACTUAL EXAM 120
QUESTIONS AND CORRECT DETAILED ANSWERS
WITH RATIONALES (100% VERIFIED ANSWERS)
|ALREADY GRADED
Question 1. For CD8+ T lymphocytes to recognize virally infected cells, the infected
cells must —
A. express functional HLA-DM molecules.
B. express functional t...
B. Activation of TLR9 expressed by CD41 cells inhibits generation of TH2 cytokines.
C. Activation of TLR9 expressed by dendritic cells inhibits TH2 cell generation of
cytokines.
D. Activation of TLR9 expressed by endothelial cells inhibits recruitment of TH2 cells to
sites of allergic inflammation. - Answer✔️✔️-1. Answer: C
Explanation: Because TLRs are highly expressed on dendritic cells but not on T cells,
the goal of TLR-based therapies in patients with allergy and asthma is to activate
dendritic cells to produce a cytokine milieu (eg, IL-12 and interferons) that favors
inhibition of the TH2 immune response.
Question 2. Which of the following human diseases is primarily caused by a defect in
the innate immune system?
A. IL-1 receptor-associated kinase 4 (IRAK4) deficiency
B. severe combined immunodeficiency (SCID)
C. X-linked agammaglobulinemia (XLA)
D. DiGeorge syndrome - Answer✔️✔️-2. Answer: A
Explanation: IRAK4 deficiency is a novel primary immunodeficiency specifically affecting
TLR function, which is a component of the innate immune system. IRAK4 is involved in
downstream signaling from most TLRs.
Question 3. One recognition strategy used by the innate immune system is to detect
conserved microbial components. Which of the following is an example of a well-
characterized innate im- mune system receptor-ligand pair?
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller EmillyCharlotte. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $12.49. You're not tied to anything after your purchase.
