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PC707 Exam 2 Questions And 100% Correct Answers
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PC707 Exam 2 Questions And 100% Correct AnswersDrug class that crosses placental membranes and are deposited in fetal teeth and
bones, may cause intrauterine growth restriction. - Answer Tetracyclines
MOA: drug class that interferes with production of protein by competitive binding to the
RNA ribosome inhibiting the actions of growth and repair - Answer Tetracyclines
MOA: drug class that works by interfering with DNA gyrase which is the enzyme
responsible for stranding of bacterial DNA synthesis, as well as bacterial growth and
replication. They are bacterialcidial - Answer Fluroquinolones
Fluroquinolones should not be used in children under the age of? - Answer 18
what is the Black box warning for fluroquinolones? - Answer tendon rupture
what is the most commonly used drug class used in pregnancy? - Answer antibiotics?
what is the most common bacterial infection in pregnancy? - Answer UTI
MOA: weakening the organisms cell wall, causing excessive amount of water to be taken
up, and rupturing the cell wall. thus disrupting cell wall synthesis, and promoting its
destruction - Answer Penicillins
Are Penicillins safe during pregnancy and breastfeeding? - Answer yes, if needed
MOA: this class of medication controls the development of reproduction of bacteria and
inhibit protein synthesis. -Answer Macrolides
,Identify one Macrolide that is not safe for Pt's with Prolonged QT syndrome. -Answer
Azithromycin
Are macrolides safe during pregnancy and breastfeeding? -Answer yes, if needed
MOA: interferes with cell wall synthesis -Answer Cephalosporins
What is the biggest contraindication when considering a Cephalosporin (keflex)?
-Answar a Pt with a severe PNC allergy.
Are cephalosporins (Keflex) safe during pregnancy? -Answar yes, if needed
MOA: inhibits protein synthesis by interacting with DNA and causing a loss of helical
DNA structure and strand breakage. -Answar Metronidazole (antibiotic)
What is the black box warning for Metronidazole? -Answer its shown to be a carcinogen
in mice and rats
Is Metronidazole safe in pregnancy and what is it used for? -Answer yes, and for BV
Is metronidazole safe during breast feeding? -Answer not reccommended
What trimesters of pregnancy should you not use a Sulfonomide (Bactrim)? -Answer 1st
and 3rd
is it safe to use sulfonomides (Bactrim) while breast feeding? - Answer No
what are sulfonomides not used in children under the age of 2 and while breastfeeding?
- Answer it can cause kernicterus and hyperbilirubinemia
, MOA: inhibition of folate meabolism, which may lead to cardiovascular defect and oral
cleft defects. - Answer Sulfonomides (Bactrim)
When is Macrobid not safe during pregnancy? - Answer Week 38-42 or while in labor
MOA: damaged bacterial DNA - Answer Macrobid
what are the gram positive bacteria - Answer Staph, Strep and Enterococci
Name a Narrow Spectrum Penicillin - Answer Pen G
What types of bacteria dose Pen G target? - Answer mostly gram +
except a penicillinase-producing staphlococci
Drug class: Pen G - Answer Penicillin
Describe the MOA of the Penicillin class: 3 key points - Answer weaken cell wall
take up excess amount of fluid (burst)
bactericidial
name 3 side affects to Penicillin's (Pen G) - Answer most common drug allergy
pain at site (IM)
sensory motor dysfunction
what caution should you take in a Pt with a PNC allergy? - Answer Prescribing a
Cephalosporin
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