Exam (elaborations)
MRCP - Pharmacology Part 1 (Toxicity) Exam Questions and Answers (Latest Update 2024)
- Course
- Institution
MRCP - Pharmacology Part 1 (Toxicity) Exam Questions and Answers (Latest Update 2024)
[Show more]
Content preview
MRCP - Pharmacology Part 1 (Toxicity)Exam Questions and Answers (Latest
Update 2024)
What monitoring do you need for statins? - Correct Answer
✅ LFTs at baseline, 3 mo and 12 mo
An AST rise of what level is enough to discontinue a statin?
What do you do? - Correct Answer ✅ If AST goes up x3
from baseline and persists. Stop the statin and restart at a
lower dose if symptoms resolve
What monitoring do you need for ACE-I? What is an
acceptable change in function? - Correct Answer ✅ - U&E
at start, when increasing treatment or annually
- Rise in creatinine up to 30%, and K+ up to 5.5mol is allowed
What monitoring do you need for amiodarone? (4/2) -
Correct Answer ✅ - TFTs, U&E, LFTs and CXR prior to
treatment
- TFTs and LFTs at 6 months
,MRCP - Pharmacology Part 1 (Toxicity)
Exam Questions and Answers (Latest
Update 2024)
What happens if amiodarone causes hypothyroidism? -
Correct Answer ✅ Continue it if required and add
levothyroxine
What are the two types of amiodarone induced
hyperthyroidism? - Correct Answer ✅ - AIT1 = excess
iodine causes a goitre and therefore tx with carbimazole
- AIT2 = destructive thyroiditis due to amiodarone = no goitre
and tx with steroids
What monitoring do you need for methotrexate? (3) - Correct
Answer ✅ - Check LFTs, FBC & U&E before treatment, and
then every two weeks for 2 months, then every month then
every 3 months
What drug needs to be given with methotrexate? - Correct
Answer ✅ Folate 5mg on a separate day
When does lithium level need to be taken? - Correct Answer
✅ 12h after the dose when starting the drug, at each dose
change and at 3 months
,MRCP - Pharmacology Part 1 (Toxicity)
Exam Questions and Answers (Latest
Update 2024)
What is a normal lithium level? - Correct Answer ✅ 0.4-0.8
Apart from lithium level, what blood tests need to be done for
monitoring lithium? (2) - Correct Answer ✅ TFTs/U&E at
baseline and 6 months
What montoring is needed for Glitazones? - Correct Answer
✅ LFTs
What monitoring is needed for olanzapine? - Correct
Answer ✅ CBG at baseline and regular intervals
What monitoring is needed for vitamin D? - Correct Answer
✅ Calcium levels at 1 month and vitamin D
- if Vit D >50 = okay
- if Vit D25-50 = deficient for some of the population
- if Vit D <25 = deficient
, MRCP - Pharmacology Part 1 (Toxicity)
Exam Questions and Answers (Latest
Update 2024)
What monitoring, and when, is needed for levothyroxine? -
Correct Answer ✅ - Check TFTs in 6-8 weeks
- Check yearly if on maintenance dose
What monitoring is needed for carbimazole or clozapine? -
Correct Answer ✅ FBC = risk of agranulocytosis
When do you need to check the dose of Gentamicin? What
time of killing does it have? How do you alter the dose -
Correct Answer ✅ Concentration dependant killing
- Check peak level 1h after the 3rd dose and trough level
before next dose
- Peak level should be 3-5
- Trough level should be <1
As concentration dependant killing, ;need to alter the time
between each dose if trough level is raised BUT need to lower
dose if the peak level is high
C/G like DNA base pairs
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Allivia. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $13.49. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
75632 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now