Pegfilgrastim - Neulasta - ANSWER1 dose each cycle > 24 hours after chemo
Potential cardiovascular toxicities in a client receiving tx for cancer - ANSWER1- alteration in the electrical conduction within the heart.
2. cardiomyopathy as the most common chronic cardiac toxicity
Asymptomati...
Pegfilgrastim - Neulasta - ANSWER1 dose each cycle > 24 hours after chemo
Potential cardiovascular toxicities in a client receiving tx for cancer - ANSWER1- alteration in the
electrical conduction within the heart.
2. cardiomyopathy as the most common chronic cardiac toxicity
Asymptomatic bradycardia is likely to related to which of the following chemo agents - ANSWERPaclitaxel
(Paxen, Taxol)
Factors that are associated with increased risk of cardiotoxicity from chemo include - ANSWER1 high-
dose cyclophosphamide, RT to the chest, and multiple cardiotoxic drugs
2. high doses o potentially cardiotoxic chemo agents administered over relatively short periods of time.
Prevention of doxorubicin related cardiomyopathy includes - ANSWERexercise ad use of dexrazoxane
When the ejection fraction is less than 45% the nurse should expect - ANSWERdecrease in the dose of
cardiotoxic chemo agents
Which statements correctly identify the classification of chemo agents and their potential effects -
ANSWER1 Antimetabolites have the potential to cause coronary artery spasm, resulting in cardiac
related sudden death
2 Taxanes and some alkylating agents can cause early heart failure and left ventricular dysfunction
A client admitted with CHF. Records indicate hx of breast cancer treated with chemo and RT. The most
likely late effect of this treatment is - ANSWERcardiomyopathy caused by anthracycline therapy
major difference between the short acting and intermidiate and long acting corticosterioids -
ANSWERShort acting have greater sodium and water retention activity.
The major advantage of intermediate-
, which of the following places anticancer drugs appropriately in terms of emetogenic potential?
1 . paclitaxel, ifosfomide greater than 2g/m2, and bulsufan - moderate
2. vinorelbine, vincristine and etoposide - low
3. bleomycin, docetaxel and melphalan - very low
4. Dacarbazine and doxorubicin/cyclophoasmide high - ANSWER4
One reason for administering 20mg of IV dex before chemo regimen - paclitaxel and carboplatin is to:
1. prevent allergic reaction to cisplatin
2. stimulate appetite after chemo
3. improve antiemetic efficacy
4. decrease the chance of chemo induced diarrhea - ANSWER3
Docetaxel, Paclitaxel - ANSWERdex given to prevent hypersensitivity
Effect antiemetic regimen for Doxorubicin and Cisplatin - ANSWER5 HT3 antigonist plus dexamethasone
and sometimes P-neurokinin-1
The serotonin antagonists include - ANSWERondansetron
(Zofran), granisetron, dolasetron, and palonosetron; they are antagonists,.
D2 antagonist - ANSWERProchlorperazine
metoclopramide and phenothiazines
Extrapyramidal s/e
NK-1 antagonist - ANSWERAprepitant
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