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COMSAE ALL QUESTIONS AND ANSWERS 100% GUARANTEED SUCCESS. COCAINE intoxication - correct red judgement, pupil dilate, hallucination (coke bugs) sudden cardiac death; paranoid ideations, angina Tx: alpha blockers/ benzos caution B block bc can cause unopposed alpha Osteoporosis hi...

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  • September 13, 2024
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  • 2024/2025
  • Exam (elaborations)
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COCAINE intoxication - correct answer.impaired judgement, pupil dilate, hallucination
(coke bugs) sudden cardiac death; paranoid ideations, angina

Tx: alpha blockers/ benzos
caution B block bc can cause unopposed alpha

Osteoporosis histo - correct answer.trabecular and cortical bone lose mass and
interconnection despite normal bone mineralization

assoc w/ Colles fracture- distal radial fracture; fracture of femoral neck

Gilbert Syndrome - correct answer.mild dec UDP glucuronosyltransferase conjugation
and impaired bilirubin uptake; asymptomatic or mild jaundice>> inc unconjugated
bilirubin w/o hemolysis; w/ fasting and stress

Crigler Najjar - correct answer.ABSENT UDP glucuronsyltransferase; early in life; die
few years

find: jaundice, kernicterus (in brain) inc unconjugated bilirubin;

tx: plasmapheresis and phototherapy; type II respond phenobarbital

Dubin Johnson - correct answer.Conjugated hyperbilirubinemia b/c defective liver
excretion;
grossly black liver
Benign

Rotor syndrome - correct answer.milder in presentation w/o black liver

impaired hepatic uptake and excretion

,wilson Disease - correct answer.copper transporting ATPase; ATP7B on Chromosome
13

s/s: before 40 yo, liver dz, neurodisease, psych dz, Kayser Fleischer ring, hemolytic
anemia, renal dz;
find: dec serum ceruloplasmin, inc urine copper
tx: chelation w/ penicillamine or Tridentine, oral zinc

Hemochromatosis - correct answer.recessive, HFE, chromosome 6; abnormal iron
sensing, increase intestinal absorb

find: inc ferritin, inc iron, dec TIBC, inc transferrin saturation
identify w/ Prussian blue stain/ liver MRI

Hemochromatosis finds - correct answer.after age 40
>20 iron;
triad: cirrhosis, DM, skin pigmentation; dilated cardiomyopathy, hypogonadism,
arhtropathy; HCC is common cause death

Treatment Hemochromatosis - correct answer.repeat phlebotomy, chelation
deferasirox, deferoxamine, oral deferiprone

Wolff Parkinson White Syndrome - correct answer.MC ventricular pre excitation
syndrome

abnml fast atria to ventricle (bundle of Kent); bypasses AV node>> ventricles begin
partially depolarization earlier (NOTED BY DELTA WAVE ON EKG) widened QRS and
shortened PR

Conduction pathway heart - correct answer.SA node> atira> AV node> bundle HIS, R
and L bundle branches> purkinje fibers> ventricles

L branch anterior/posterior fascicles

Edema - correct answer.inc capillary pressure
dec plasma proteins (dec oncotic capillary pressure)
inc capillary permeability
increase interstitial fluid colloid oncotic pressure

Celiac Disease - correct answer.setting: 14 mo kid losing weight eating lots of foods;

histology: crypt abnormalities (hyperplasia); villous atrophy, lymphocytic infiltration

presents as malabsorbtion (diarrhea etc in kids)
in adults= short stature, anemia delayed puberty

, Musculocutaneous nerve C5-C7 - correct answer.upper trunk compression cause
injury; loss forearm flexion/supination; loss sensation over lateral forearm

Axillary nerve C5-C6 - correct answer.flat deltoid; loss arm abduction, loss sensation
over deltoid and lateral arm

Radial C5-T1 - correct answer.mid shaft fracture humerus, compression axilla

find: dec grip, loss extension (wrist drop); loss sensation posterior arm, dorsal hand

Median C5-T1 - correct answer.supracondylar fracture humerus (proximal) CTS, wrist
laceration (distal)

ape hand pope's blessing

loss wrist flexion, flex of lateral fingers, thumb opposition, lumbricals 2nd and 3rd digit;
loss sensation over thenar eminence and dorsal and palmar aspects of lateral 3 1/2
fingers w/ proximal

Ulnar C8-T1 - correct answer.Fracture medial epicondyle humerus; fractured hook
hamate (distal lesion)

ulnar claw on extension; radial deception wrist upon flexion (proximal lesion)

loss wrist flex, flex of medial fingers, abduction and adduction fingers; medial 2
lumbricals;
loss sensation over 1 1/2 fingers including hypothenar eminence

Recurrent branch median nerve - correct answer.superficial laceration palm

ape hand; loss thenar muscles
no loss sensation

Treatment glaucoma: alpha agonists; epinephrine, brimonidine - correct answer.dec AH
synthesis> vasoconstriction; mydriasis alpha 1 (don't use in closed angle glaucoma)
blurry vision, ocular hyperemia, foreign body sensations ocular allergy, pruritis

Beta blockers: timolol, betaxolol, carteolol - correct answer.dec AH synthesis; no
pupil/vision changes

Diuretics; acetazolamide - correct answer.dec AH synthesis by inhibiting carbonic
anhydrase; no vision/pupil change

Cholinomimetics M3; direct pilocarpine carbachol; indirect physostigmine,
echothiophate - correct answer.inc outflow of AH via contraction of ciliary muscle/open
trabecular mesh; pilocarpine in ER--very effective open meshwork into Canal schlemm,

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