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Red Blood Cells Exam Questions and Answers 2024/2025( A+ GRADED 100% VERIFIED).
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Red Blood Cells Exam Questions and Answers 2024/2025( A+ GRADED 100% VERIFIED).
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Red Blood CellsRed Blood Cells (RBCs)
Biconcave disk shape (called discocyte, phospholipid membrane allows for
flexibility) of 6-8 um in diameter.
No nuclei/organelles, but do have limited metabolic functions.
Zone of slight central pallor not exceeding 1/3 the diameter of the cell.
Described as normochromic, normocytic.
Survive 100-120 days.
Function of RBCs
Deliver oxygen via hemoglobin.
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RBC Development
Results in decreased size and eventual loss of the nucleus.
Hemoglobin production causes increasing redness of cytoplasm.
Reticulocyte
, Final stage prior to mature RBC.
Most immature form found in peripheral blood.
Has some residual RNA but no nucleus.
Slightly larger and more basophilic.
Normal RBCs
Erythropoiesis in Fetus
Liver is the main site of production of RBCs at this stage.
Erythropoiesis in Children
All of the skeletons are active in production of RBCs at this stage.
Erythropoiesis in Adults
Axial skeleton is the main site of production of RBCs at this stage.
Increased Demand for RBCs
Causes conversion of fatty marrow to active marrow.
Causes increased marrow cellularity and RBC production (7-8 fold increase).
Often seen in anemia.
Extramedullary Hematopoiesis
RBC, granulocyte, or platelet production in liver or spleen.
Occurs when marrow cannot compensate for need.
Mainly seen in myeloproliferative diseases, also severe anemia.
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