NR565 FINAL EXAM/NR 565 ADVANCED
PHARMACOLOGY CARE OF THE
FUNDAMENTALS EXAM 2023-2024 ACTUAL
EXAM 100 QUESTIONS AND CORRECT DETAILED
ANSWERS
Terms in this set (106)
What labs are used to 1. Serum thyroid-stimulating hormone test (TSH)
diagnose thyroid 2. Serum thyroxine test (Total or Free T4)
function? 3. Serum triiodothyronine test (Total or Free T3)
Signs and symptoms of hypothyroidism depend on
disease severity. The face is pale, puffy, and
expressionless; skin is cold and dry; hair is brittle; hair
s/s hypothyroidism
loss occurs;Heart rate and temperature are lowered.
The patient may complain of lethargy, fatigue, and
intolerance to cold. Mentation may be impaired.
Exophthalmos; Heartbeat is rapid and strong;
dysrhythmias and angina may develop; nervousness;
insomnia, rapid thought flow; rapid speech; Skeletal
muscles may weaken and atrophy; Metabolic rate is
s/s hyperthyroidism
raised, resulting in increased heat production,
increased body temperature, intolerance to heat, and
skin that is warm and moist. Appetite is increased, but
weight loss may still occur.
When should you re- TSH 6-8 weeks after initiation or dose changes.
check labs after initiating
Levothyroxine?
, profound hyperthermia (105°F or even higher), severe
tachycardia, restlessness, agitation, and tremor.
S/S of Thyrotoxic Crisis Unconsciousness, coma, hypotension, and heart
(Thyroid Storm) failure may occur
*Excessive levels of thyroid hormones (occurs after
surgery or intercurrent illness (e.g. sepsis)
MEDICAL EMERGENCY
1.High doses of potassium iodide or strong iodine
solution are given to suppress thyroid hormone
release.
Treatment of thyroid storm 2.Methimazole is given to suppress thyroid hormone
synthesis. 3.A β-blocker is given to reduce heart rate.
Additional measures include sedation, cooling, and
giving glucocorticoids and IV fluids.
What can result from not permanent neuropsychological deficits in the child
treating hypothyroidism
during pregnancy?
1. surgical removal of thyroid tissue
2. destruction of thyroid tissue with radioactive iodine
(preferred for adults)
3. antithyroid drug (methimazole or propylthiouracil).
Treatment of (preferred for younger patients)
hyperthyroidism
β-Blockers suppress tachycardia by blocking β-
receptors on the heart.
Nonradioactive iodine inhibits synthesis and release of
thyroid hormones.
Food interactions with Food decreases absorption. Should be taken on an
levothyroxine empty stomach 30-60 minutes prior to breakfast
phenytoin (Dilantin)
carbamazepine (Tegretol, Carbatrol)
rifampin (Rifadin)
sertraline (Zoloft)
phenobarbital.
Drugs that accelerate
levothyroxine metabolism *To maintain adequate levothyroxine levels, patients
taking these drugs may need to increase their
levothyroxine dosage.
*Digoxin and Insulin may have more requirements
when taking levothyroxine
free triiodothyronine (T3)
Which laboratory tests
free thyroxine (T4)
should be completed
LFTs
before prescribing
thyroid-stimulating hormone (TSH)
methimazole?
CBC
Which agent is the PTU (propylthiouracil)
preferred treatment
option for thyroid storm?
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