Acute intermittent porphyria
-SX
- Gene dominant?
- Who does it effect
- Labs
- Urine?
Abdominal crisis, CNS dysfunction, Fever
HYPONATREMIA
Autosomal Dominant (Inherited)
Young women
**Urine is normal in color but once exposed to light and air it turns dark - Increased Amount of ...
Acute intermittent porphyria
-SX
- Gene dominant?
- Who does it effect
- Labs
- Urine? - ANSWER- Abdominal crisis, CNS dysfunction, Fever
HYPONATREMIA
Autosomal Dominant (Inherited)
Young women
**Urine is normal in color but once exposed to light and air it turns dark -
Increased Amount of porphobilinogen
What can cause AIP - ANSWER- Starvation diets
fasting
Sulfas
Treatment for AIP - ANSWER- High carb diet
300mg/day
Downs Trisomy - ANSWER- Trisomy 21
advanced maternal age
There are approximately 6,000 babies born with Down's every year in the United
States. This works out to be about one in every 700 births.
,Lab to test for recurrence of downs in furture offspring - ANSWER- Cytogenomic
Analysis
What Hepatitis can cause chronic infections - ANSWER- B, C, D
What Hepatitisis have vaccines to prevent Disease/ - ANSWER- A and B
What hepatits presents with diarrhea - ANSWER- Hep A and E
Lab for Hep A - ANSWER- IgM antibody test (ANTI-HAV)
NAAT (anti-HHV IIG)
How is Hep A spread - ANSWER- Fecal and oral
Food and water
Incubation period of Hep a - ANSWER- 28 days
If you have Hep A can you get it again? - ANSWER- No, once you have it you have
lifelong Antibodies to it
Who is high risk for Hep A - ANSWER- International Travler
MSM
Homelessness
People in contact with international adoptee
Hep A Vaccine - ANSWER- 2 part series
Given to pt >12 months of age
Preferred tx of Hep A - ANSWER- age 12-40 = Vaccine
>40 = immunoglobulin
Self Limiting 2-6 mths
Hep B Symptoms and age - ANSWER- Sx show up in children > 5 yrs
Sx of Hep B - ANSWER- Chronic may not have sx.
, Joint pain
Jaundice
fever
abd pain
Clay colored stools
dark urine
fatigue
How is hep B spread - ANSWER- Blood and body fluids
Semen, saliva, blood
Way Hep B is not spread - ANSWER- Hugging
kissing
hand holding
sneexing
coughing
breast feeding
use of same water source
utensils
Who is is at increased risk of Hep B infections - ANSWER- Infants of + mothers
MSM
HIV
Occupational exposure
Hemodialysis patients
Incubation period for Hep B - ANSWER- 90 days
Tx for Hep B - ANSWER- 95% of pts recover fully
Vaccine at birth
"VIR" Tx
Once you have Hep B can you get it again - ANSWER- No but it can be chronic
Does hep C have Vaccine - ANSWER- no
Can Hep C be Chronic - ANSWER- Yes
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