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NBME CBSE ACTUAL TEST QUIZ BANK 2024/2025| REAL EXAM QUESTIONS AND 100% CORRECT DETAILED ANSWERS (USMLE STEP 1) MEDICAL EXAMINATION ;COMPLETE SOLUTION NBME CBSE ACTUAL TEST QUIZ BANK 2024/2025| REAL EXAM QUESTIONS AND 100% CORRECT DETAILED ANSWERS (USMLE STEP 1) MEDICAL EXAMINATION ;COMPLETE SOLUT...

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NBME CBSE ACTUAL TEST QUIZ BANK 2024/2025|
REAL EXAM QUESTIONS AND 100% CORRECT
DETAILED ANSWERS (USMLE STEP 1) MEDICAL
EXAMINATION




62 iyear iold iwoman i- iosteoporosis i- ia ibisphosphonate iis iprescribed. iThe iexpected ibeneficial ieffect iof
ithe idrug iis idue ito iwhich iof ithe ifollowing? i- icorrect iAnswers i✔✔ i-Decreased iOsteoclast iActivity


Cohot iStudy iof ielderly iwomen i- irelative irisk iratio ifor ihip ifractures iamong ithose iwho iexercise
iregularly iis i1.2 i(95% iconfidence iinterval iof i1.1 ito i1.8). iWhich iof ithe ifollowing iis ithe iconclusion

iabout ithe ieffect iof iexercise ion ithe irisk iof ihip ifracture? i- icorrect iAnswers i✔✔ i-Statistically
iSignificant iOverall iIncrease iRisk


52 iyear iold iman igoes ito iER iwith ichest ipain iradiating ito ihis ijaw iwhile ishoveling isnow. iPulse iis
i80/min iand iblood ipressure iis i130/70. iThe imost iimmediate itreatment imechanism iof iaction? i-

icorrect iAnswers i✔✔ i-Increased initric ioxide iconcentration


24 iyear iold iwoman i- ispilled ihot igrease ion iher ileft ileg iwhile iworking iat ia ifast-food irestaurant. iExam
iof ileg ishows i7cm ipink, isoft, igranular, iedematous iwound. iThe iformation iof ithis itissue iwas imost
ilikely icaused iby iincreased iactivity iof iwhich? i- icorrect iAnswers i✔✔ i-a. iVascular iEndothelial iGrowth
iFactor


VEGF i- istimulates iangiogenesiss.

TYPE iIII iCollagen i= iBlood iVessels i- iearly iwound irepair

27 iyear iold iman- iMVC i- iskull ix-ray ishows ia ilinear, inondepressed ibasal iskull ifracture i- iincreased
iserum iosm iand idecreased iurin iosm. iFollowing idesmopressin iurine iosm iincreases. iDesmopressin's

ieffect iis idue ito ithe iactivation iof iwhich iof ithe ifollowing? i- icorrect iAnswers i✔✔ i-a. iAdenylyl iCyclase


iAdenylate iCyclase i- iATP i- iCAMP i-- iPROTEKINASE iA i-- iCa


v2

,A i10 imonth iold iboy i- i4 iday ihistory iof ifever iand icough. iHe iattends iday icare icenter. iChest iexam
ishows iintercostal iretractions ialong iwith ibilateral, idiffuse iwheezes iand iexpiratory irhonchi. iThe
iinfectious iagent imost ilikely ihas iwhich iof ithe ifollowing iproperties? i- icorrect iAnswers i✔✔ i-
Mediation iof iCell iEntry ivia ia ifusion iprotein

A i17 iyear iold igirl iin iED i- i15 iminutes iafter ibeing istung iby ia ibee. iMild ilight iheadedness ibut ino
idifficulty iswallowing- iBilateral iwheezing i- iWhich iis imost iappropriate ipharmacotherapy ifor ithis
ipatient? i- icorrect iAnswers i✔✔ i-B2- iAgonist


14 iyear iold iboy i- i2 iday ihistory iof isore ithroat iand ifever ithat ipeaks iin ilate iafternoon. i1 iweek iof
ifatigue. iHe irecentaly ihad isex iwith ione ipartner. iPhysical iexam ishow icervical ilymphadenopathy iand

ipharyngeal ierythema iwith ia icreamy iexudate. iDX? i- icorrect iAnswers i✔✔ i-Infectious iMononucleosis


57 iyear iold iman i- iradiation itherapy ifor isquamous icell icarcinoma iof ithe ilung. iDespite itherapy, itumor
iincreases iin isize iand ihe idies i6 imonths ilater. iThe iprogressive itumor igrowth iis idue ito ia idefect iin icell
icycle iarrest iin iwhich iof ithe ifollowing iphases iof icell icycle? i- icorrect iAnswers i✔✔ i-G1


28 iyear iold i- ilived iin isub-Saharan iAfrica i- iuntil ihe icame ito ithe iUS. iTemp iof i100.4 i- iimaging ishows
ibilateral ihydroureter iand ihydronephrosis. iBiopsy ishows imarked ifibrosis iand iscattered igranulomas.

iDX? i- icorrect iAnswers i✔✔ i-Schistosomiasis


A icouple iwith ia ifamily ihistory iof ia-thalassemia. iWoman ihas ione igene ideletion iand iman ihas itwo
igene ideletion. iIf ithe itwo igene iis itrans i- iwhat ipercentage iof ioffspring iwill ihave ia itwo igene

ideletion? i- icorrect iAnswers i✔✔ i-50%


previously ihealthy i40 iyear ibrought ito iemergency idepartment iby iher ihusband i- i2 iday ihistory iof
ifever, ilethargy, iconfusion. iPE ishows iscattered ipetechiae iand iecchymoses iover ithe ilower iextremities
i- i3+ ipolychromasia iand i3+ ischistocytes iand iLow iplatelets iDx? i- icorrect iAnswers i✔✔ i-Thrombotic
iThrombocytopenia iPurpura


16 iyear iold iboy i- iis iadmitted ito ithe iER ibecause iof ia iknife iwound ito ithe ileft iside iof ihis ichest. iAn iX-
ray iof ithe ichest ishows ian iair-fluid ilevel iin ithe ileft iside iof ithe ichest, ipartial icollapse iof ithe ileft ilung,
iand ithe ielevation iof ithe istomach ibubble. iThe imediastinum iis imidline. iDX? i- icorrect iAnswers i✔✔ i-
Hemopneumpothorax iunder itension

49 iyear iold iwoman i- icoronary iartery idisease i- iBP i140/90 i- iHigh iCholesterol, iHigh iLDL i(190), iHigh
itriglycerides i(350) i- iTX iwith iatorvastatin iand ilosartan. iWhat iare ithe ieffects ion iHDL iand

iTriglycerides? i- icorrect iAnswers i✔✔ i-HDL iincreased


Triglycerides iDecreased

73 iyeare iold i- idiffuse iweakness iand itingling iof iher iarms iand ilegs. iSensation iand ivibration iand
iposition iis idecreased iin iall iextremities. iWhat ivitamin ideficiency? i- icorrect iAnswers i✔✔ i-Vitamin
iB12 i- i(cyanocobalamin)

,Tea iand iToast i- ilow iB12 iin idiet

15 iyear iold igirl i- i3 imonth ihistory iof iacne i- iwhich iis ithe iunderlying icause iof ithe ipatients iacne? i-
icorrect iAnswers i✔✔ i-Stimulation iof iSebaceous iGlands iby iandrogens


b. iACNE i= iPropionibacterium iACNE

4 iyear iold ifrom iBrazil i- iPE ishows isingle i12x10cm ilesion iin ithe iright iside iof ijaw iwith idiffuse iregular
iedges. iPhotomicrographs iof ian iincisional ibiopsy i(looks ilike iBurkitts iLymphoma/ iStarry inight) i- iwhich

iof ithe iprocesses imost ilikely ito ioccur iin ithe iregion iindicated iby ithe iarrow? i- icorrect iAnswers i✔✔ i-
Apoptosis

b. iEndemic iBurkitt ilymphoma ican ihappen iin iBrazil ias iwell ias iAfrica i(jaw ilesion, ipuffy iface).

51 iyear iold i- ilump ion itongue i- i1 ipack ismoking ihistory ifor i30 iyears. i1.5 icm imass ion iapex iof itongue.
iIt iis imost iappropriate ito ievaluate iwhich ilymph inodes ifirst ifor ievidence iof imetastasis? i- icorrect
iAnswers i✔✔ i-Submental


15 iyear iold iboy i- iER i- i2 ihour ihistory iof iconfusion iand iagitation i- ifever, iheadache, istiff ineck, iand
ivomiting i- isince ireturned ifrom isummer icamp i- ipatient iis ihallucinating i- ilumbar ipuncture i- ishows

icysts iand itrophozoites- imost ilikely ipathogen? i- icorrect iAnswers i✔✔ i-a. iOlfactory iNerve


Naegleria ifowleri

17 iyear iold i- iED i- i30 iminutes iafter ibeing ifound iwith ia iblank istare. iPhysical iexam ishows irigidity.
iDuring iexam ihe ibecomes ihostile iand iassaults iphysician i- iPt iingested iwhich idrug? i- icorrect iAnswers i

✔✔ i-PCP

Placebo icontrolled iclinical itrial i- i5000 ipts iwith iessential ihypertension. i2500 ipatients ireceive inew
idrug iand i2500 ipatients ireceive iplacebo. iIf ialpha iis iset iat i0.01 iinstead iof i0.05, iwhich iof ithe
ifollowing iis imost ilikely iresult? i- icorrect iAnswers i✔✔ i-Significant ifindings ican ibe ireported iwith
igreater iconfidence


17 iyear iold i- igymnast i- icomes ito ihospital ibecause iof ilack iof imenstrual iperiod ifor i6 imonths. iBMI i15
iWhich iis ithe icause iof ithe iamenorrhea? i- icorrect iAnswers i✔✔ i-Hypogonadotropic iHypogonadism


A imale istillborn iis idelivered iat i32 iweeks i- iOligohydramnios i- iabsence iof ia iurethral iopening. iWhich
iis imost ilikely ifinding? i- icorrect iAnswers i✔✔ i-Pulmonary iHypoplasia


A i6 iday iold i- ibreast ifed iboy iin iED i- ipoor iweight igain iand iirritability isince idelivery i- iPhysical iexam
ishows ijaundice iand ihepatomegaly. iThe iconcentration iof iwhich iof ithe ifollowing imetabolites iis imost

ilikely iincreased? i- icorrect iAnswers i✔✔ i-a. iGalactose i- i1 i- iphosphate


b. iCongenital iintolerance ito ibreast imilk

, A i25-year-old iman i- icomes ito iED i- isevere imuscle ipain, idiffuse, ipainful iswelling iof ihis ineck,
iunderarms, iand igroin iafter icamping iin iNew iMexico iGeneralized iscattered iblack imaculae.
iExamination iof ithe iright iupper iextremity ishows ierythematous, isolid, itender imass. iMass iis idraining
iblood iand inecrotic imaterial. iThe imost ieffective iantibiotic ifor ipatient idisorder iwill iinterfere iwith

iwhich iof ithe ifollowing iprocesses? i- icorrect iAnswers i✔✔ i-a. iRibosomal iAssembly


b. iYersenia iPestis

45 iyear iold i- iprogressive iweakness i- imuscle ifasciculations iof ithe iupper iextremities iand iweakness iof
ithe ilower iextremity i- iWhat iadditional ifindings? i- icorrect iAnswers i✔✔ i-Atrophy


b. iALS i= iLou iGherig

A inew isevere irespiratory iillness i- iWhy iuse ia ikilled ivaccine ivs ia ilive ivaccine? i- icorrect iAnswers i✔✔
i-Avoids iConcerns iof ireversion ito ivirulence


b. iKilled ivaccines i- iavoids ireversion ito ivirulence

c. ilive ivaccines i- ican i(but irarely ido) icause ithe idisease ithey're idesigned ito iprevent

A i33 iyear iold i- ikeratinizing isquamous icell icarcinoma iof icervix. iWhich iof ithe ifollowing idescribes
ipathogenesis iof ithis ipatient's idisease? i- icorrect iAnswers i✔✔ i-Inactivation iof iCellular iP53


b. ip53 iprotein i= itumor isuppressor i(it iactivates iapoptosis) i- imost ihuman icancer

A i54 iyear iold i- i40 iyear ihistory iof iT1DM i- ireceiving ihemodialysis ifor iend istage irenal idisease iwhile
iawaiting ia ikidney itransplant. iReceives ia idrug ithat iinduces ireticulocyte irelease ifrom ibone imarrow
iand istimulates ia icytokine ireceptor ithat isignals iJak/Stat ipathway? i- icorrect iAnswers i✔✔ i-
Erythropoietin

Jak iStat i- ierythropoietin

During ia iclinical istudy iexamining ithe ieffects iof iexercise. iThe iaverage ipulse iis i175/min. iCompared
iwith imeasurement ibefore ithe isession, iwhich iis imost ilikely idecreased? i- icorrect iAnswers i✔✔ i-Total
iPeripheral iResistance


An i8-year-old iboy i- i3-day ihistory iof ifever, isore ithroat, iand iitchy ieyes. iReturned ifrom iweek ilong
isummer icamp ithat iincludes ihiking itrips iand iswimming i- iPE ishows iconjunctival iinjection iand
ioropharyngeal iedema i- iOutbreak iamong iother icampers. iWhich iis imost ilikely icause iof ithis ipatient's

isymptoms? i- icorrect iAnswers i✔✔ i-Adenovirus


Fever+ iSore iThroat i+ iItchy iEyes

transmitted ivia iswimming ipools

Conjunctivitis iViral i= iadenovirus

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