Midterm Exam: NR546/ NR 546 (New 2024/
2025 Update) Psychopharmacology for the
PMHNP Complete Review (Weeks 1-4
Covered) -Questions and Verified Answers -
100% Correct-Grade A-Chamberlain
QUESTION
IclientIwhoIisIaIpoorImetabolizer:
Answer:
hasIaIlowerIconcentrationIofItheInecessaryIenzymeItoImetabolizeIaIdrug,IwhichIresultsIinIhigh
erIbloodIconcentrationsIofItheIdrug.I
-increaseItheIriskIofIsideIeffectsIandIadverseIreactions
QUESTION
IWhyIisItrazodoneInotIusedIasIaIfront-lineIantidepressant
Answer:
ItsIantidepressantIthatIhasIaIsecondaryIeffectIofIblockingIhistamineIandIadrenergicIreceptors
-causesIsedationIandIsomnolenceIandIasIaIresult
*oftenIusedIasIanIadjunctIinItherapyIwhenIaIdepressedIpatientIhasIdifficultyIsleeping
QUESTION
IeffectIonIneurotransmittersIandIsideIeffects:ISelectiveISerotoninIReuptakeIInhibitorsI(SSRIs)
Answer:
InhibitsItheIreuptakeIofIserotonin,IwhichIcanIcauseInausea,Iagitation,Iheadache,IandIsexualIdys
function
QUESTION
,IeffectIonIneurotransmittersIandIsideIeffects:ISerotoninIandINorepinephrineIReuptakeIInhibitor
sI(SNRIs)
Answer:
InhibitsItheIreuptakeIofIserotoninIandInorepinephrine,IwhichIcanIcauseInausea,Isweating,Iinso
mnia,Itremors,IsexualIdysfunction
QUESTION
IeffectIonIneurotransmittersIandIsideIeffects:ITricyclicIAntidepressants
Answer:
-InhibitsItheIreuptakeIofIserotoninIandInorepinephrine,IwhichIcanIcauseIsexualIdysfunction
-BlocksInorepinephrineIreceptors,IwhichIcanIcauseIhypotensionIandItachycardia
-BlocksIhistamineIreceptors,IwhichIcanIcauseIsedationIandIweightIgain
-
BlocksIacetylcholineIreceptors,IwhichIcanIcauseIdryImouth,Iconstipation,IblurredIvision,IandIu
rinaryIretention
QUESTION
IeffectIonIneurotransmittersIandIsideIeffects:IMonoamineIOxidaseIInhibitorsI(MAOIs)
Answer:
IncreasesInorepinephrineIandIserotoninIbyIinhibitingItheIenzymeIthatIinactivatesIit,IwhichIcanI
causeIsedation,Idizziness,IsexualIdysfunction,IandIhypertensiveIcrisis
QUESTION
IeffectIonIneurotransmittersIandIsideIeffects:IBenzodiazepines
Answer:
IncreasesItheIreceptorIaffinityIforIGABA,IwhichIcanIcauseIdependenceIandIconfusion
QUESTION
,IeffectIonIneurotransmittersIandIsideIeffects:IBupropion
Answer:
InhibitsItheIreuptakeIofInorepinephrineIandIdopamine,IwhichIcanIcauseIinsomnia,IdryImouth,It
remors,IandIseizures
QUESTION
Iantagonist
Answer:
blocksItheIactionIofIaIneurotransmitter
QUESTION
Iagonists
Answer:
fullyIstimulateIG-protein-linkedIreceptors
QUESTION
IpartialIagonists
Answer:
stimulateIreceptorsItoIaIlesserIdegreeIthanIanIagonistIorInaturalIneurotransmitter
QUESTION
ISSRIs,ISNRIs,IandItricyclicIantidepressantsIincreaseI________Ilevels.I
___________IdoInotIimpactIserotoninIlevels.
Answer:
increaseIserotoninIlevels.I
BenzodiazepinesIdoInotIimpactIserotoninIlevels.
, QUESTION
IIsInicotineIanIinducerIorIanIinhibitorIofItheICYPI1A2Ienzyme?
Answer:
inducer
QUESTION
INicotineIisIanIinducerIofItheICYPI1A2Ienzyme.IDoesItheIPMHNPIanticipateIJoshuaImayIne
edIaIhigherIorIlowerIdoseIofIolanzapineItoIachieveIaItherapeuticIresponse?
Answer:
HigherI
-
NicotineIisIanIinducerIofItheICYPI1A2Ienzyme,IsoIitIlowersItheIconcentrationIofIdrugs.IThere
fore,IaIhigherIdoseIofIolanzapineImayIbeIneededItoIcontrolIhisIsymptoms.
QUESTION
IErnesto,IaI60-year-
old,IpresentsItoItheIPMHNPIwithIreportIofIhavingIanxiety,IfrequentIoccurrencesIofIfeelingIfro
zenIinIplaceIandIlikeIhisIheartIisIpoundingIoutIofIhisIchest,IasIwellIasIhavingIdifficultyIsleepi
ng.I
TheIPMHNPIsuspectsItheIclientIhasIanIelevatedIlevelIofIwhichIneurotransmitter?
Answer:
Norepinephrine
-responsibleIforItheIregulationIofIfightIorIflightIresponsesIandIcanIimpactImoodIandIsleep.
QUESTION
IWhichIofItheIfollowingIisItheIbestImedicationIclassIforItheIPMHNPItoIprescribeIforIErnestoI
toIaddressIhisIelevatedInorepinephrineIlevels?
Answer:
