Which of the following is a lipid-soluble hormone?
A. Cortisol
B. Oxytocin
C. Epinephrine
D. Growth hormone - answer-A. Cortisol
Most protein hormones are transported in the bloodstream and are:
A. Bound to a lipid-soluble carrier
B. Free in an unbound, water-soluble form
C. Bound to a water soluble-binding protein
D. Free because of their lipid-soluble chemistry - answer-B. Free in an unbound, water-soluble form
When insulin binds its receptors on muscle cells, an increase in glucose uptake by the muscle cells is the
result. This is an example of what type of effect by a hormone?
A. Pharmacologic
B. Permissive
C. Synergistic
D. Direct - answer-D. Direct
What imbalance lessens the rate of secretion of parathyroid hormone (PTH)?
A. Increased serum calcium levels
B. Decreased serum magnesium levels
C. Decreased levels of thyroid-stimulating hormone
D. Increased levels of thyroid-stimulating hormone - answer-A. Increased serum calcium levels
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Regulation of the release of catecholamines from the adrenal medulla is an example of which type of
regulation?
A. Negative feedback
B. Positive feedback
C. Neural
D. Physiologic - answer-C. Neural
How does a faulty negative-feedback mechanism result in a hormonal imbalance?
A. Hormones are not synthesized in response to cellular and tissue activities.
B. Decreased hormonal secretion is a response to rising hormone levels.
C. Too little hormone production is initiated.
D. Excessive hormone production results from a failure to turn off the system. - answer-D. Excessive
hormone production results from a failure to turn off the system.
Which substance is a water-soluble protein hormone?
A. Thyroxine
B. Aldosterone
C. Follicle-stimulating hormone
D. Insulin - answer-D. Insulin
Thyroid-stimulating hormone (TSH) is released to stimulate thyroid hormone (TH) and is inhibited when
plasma levels of TH are adequate. This is an example of:
A. Positive feedback
B. Negative feedback
C. Neural regulation
D. Physiologic regulation - answer-B. Negative feedback
Lipid-soluble hormone receptors are located:
A. Inside the plasma membrane in the cytoplasm
B. On the outer surface of the plasma membrane
, Page 3 of 132
C. Inside the mitochondria
D. On the inner surface of the plasma membrane - answer-A. Inside the plasma membrane in the
cytoplasm
Which second messenger is stimulated by epinephrine binding to a B-adrenergic receptor?
Which hormone does the second messenger calcium (Ca++) bind to activate phospholipase C through a
G protein?
A. Angiotensin II
B. Thyroxine
C. Estrogen
D. Testosterone - answer-A. Angiotensin II
The control of calcium in cells is important because it:
A. Is controlled by the calcium negative-feedback loop.
B. Is continuously synthesized.
C. Acts as a second messenger.
D. Carries lipid-soluble hormones in the bloodstream. - answer-C. Acts as a second messenger.
The portion of the pituitary that secretes oxytocin is:
A. Posterior
B. Inferior
C. Anterior
D. Superior - answer-A. Posterior
, Page 4 of 132
Antidiuretic hormone acts to cause vasoconstriction when:
A. Urine output is less than 20 ml/hr.
B. Serum osmolality is increased.
C. Osmotic and oncotic pressures are increased.
D. Vasopressin is pharmacologically administered. - answer-D. Vasopressin is pharmacologically
administered.
What is the target tissue for prolactin-releasing factor?
A. Hypothalamus
B. Anterior pituitary
C. Mammary glands
D. Posterior pituitary - answer-B. Anterior pituitary
Where is antidiuretic hormone (ADH) synthesized, and where does it act?
A. Hypothalamus; renal tubular cells
B. Renal tubules; renal collecting ducts
C. Anterior pituitary; posterior pituitary
D. Posterior pituitary; loop of Henle - answer-A. Hypothalamus; renal tubular cells
Where is oxytocin synthesized?
A. Hypothalamus
B. Paraventricular nuclei
C. Anterior pituitary
D. Posterior pituitary - answer-D. Posterior pituitary
The releasing hormones that are made in the hypothalamus travel to the anterior pituitary via the:
A. Vessels of the zona fasciculata
B. Infundibular stem
C. Hypophyseal stalk
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