PCB 3233 IMMUNOLOGY - EXAM 3
QUESTIONS AND ANSWERS
Which cell types can become a plasma cell? - Answer️️ -All the
above (a memory B-cell, an activated B-cell, a centrocyte
The types of human MHC II presenting molecules are: - Answer️️ -
HLA-DP, HLA-DQ, HLA-DR which present peptide to C...
PCB 3233 IMMUNOLOGY - EXAM 3
QUESTIONS AND ANSWERS
Which cell types can become a plasma cell? - Answer✔️✔️-All the
above (a memory B-cell, an activated B-cell, a centrocyte
The types of human MHC II presenting molecules are: - Answer✔️✔️-
HLA-DP, HLA-DQ, HLA-DR which present peptide to CD4 T-cells
__________ has an alpha chain and a beta chain in their structure
while ________ only has an alpha chain in its structure? -
Answer✔️✔️-MHC II, MHC I
What process(es) are used after activation to make MHC I and II
binding sites better? - Answer✔️✔️-None of the above (Somatic
recombination, somatic hypermutation, isotype switching
Burkitt's lymphoma is due to a translocation of the ________ gene
next of one of the ________ genes. - Answer✔️✔️-MYC, Ig
You would expect the IgA and IgB genes to be turned on (expressed)
during which stage/s? - Answer✔️✔️-All the above (the small pre B
cell, mature B cell, immature B cell
T-cell receptor diversity is established - Answer✔️✔️-Before antigen
stimulation
The types of human MHC I presenting molecules are: - Answer✔️✔️-
HLA-A, HLA-B and HLA-C which present peptide to CD8 T-cells
Receptor editing - Answer✔️✔️-A & B (is done on the light chain, can
be utilized in an attempt to rescue a B-cell that has a self-reactive
receptor
Which one of the following is in the correct sequence? - Answer✔️✔️-
Early Pro-B, Late Pro-B, Large Pre-B, Small Pre-B, Immature B-cell
When/where are N and P nucleotide additions added to the variable
regions (binding site? - Answer✔️✔️-During somatic recombination
Which chemokine/s call/s a B-cell into the follicle of a secondary
lymphoid tissue? - Answer✔️✔️-CXCL 13
Which cell/s is/are lymphocyte/s? - Answer✔️✔️-None of the above
(neutrophils, macrophages, dendritic cells
Which of the following is/are considered proto-oncogenes? -
Answer✔️✔️-A & B (BCL2, MYC)
A mature B-cell has: - Answer✔️✔️-IgM, IgD and IgA and IgB on the
surface
True of false: CCL19 and CCL21 direct a B-cell out of the blood
stream, across HEV's and into a secondary lymphocyte toward the
T-cell era. - Answer✔️✔️-True
2
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