VUSN Pharm 5106 Pharmacology and Diabetes. Exam Questions With Correct Answers
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Course
VUSN Pharmacology
Institution
VUSN Pharmacology
VUSN Pharm 5106 Pharmacology and
Diabetes. Exam Questions With Correct
Answers
What is Type I diabetes? - answerjuvenile onset
characterized by destruction of beta cells of the pancreas which are responsible for insulin
synthesis
significant hyperglycemia at presentation
What are some clinic...
VUSN Pharm 5106 Pharmacology and
Diabetes. Exam Questions With Correct
Answers
What is Type I diabetes? - answer✔✔juvenile onset
characterized by destruction of beta cells of the pancreas which are responsible for insulin
synthesis
significant hyperglycemia at presentation
What are some clinical signs that a child has Type I diabetes? - answer✔✔gets sick frequently
has to urinate frequently
What is insulin? - answer✔✔hormone necessary for normal carb, protein and fat metabolism
increases uptake of glucose by tissues
What organs does insulin have the greatest effect on? - answer✔✔liver
muscle
adipose tissue
What are the effects of insulin deficiency? - answer✔✔↑ glycogenolysis (generation of free
glucose from breakdown of glycogen)
↑ gluconeogensis
↓ glucose utilization
↓ cellular uptake of glucose
What is insulin therapy defined by? - answer✔✔onset, peak and duration
What is the #1 complication associated with insulin treatment? - answer✔✔hypoglycemia
What are the different types of rapid insulin? - answer✔✔Lispro (Humalog/Novalog)
What are the different types of short insulin? - answer✔✔regular (natural)
What are the different types of intermediate insulin? - answer✔✔NPH (Humulin N, Novolin N)
What are the different types of long insulin? - answer✔✔Glargine (Lantus)
Insulin Detemir (Levemir)
What are commercially mixed insulins? - answer✔✔Humulin 70/30
Humulin 50/50
Novulin 70/30
Novolog 70/30
Humalog 75/25
What insulins can be mixed? - answer✔✔NPH with humalog/regular
How should you mix NPH with humalog/regular insulin? - answer✔✔"clear to cloudy"
humalog/regular = clear
NPH = cloudy
Why do you want to mix "clear to cloudy?" - answer✔✔if humalog/regular get into NPH, patient
is still monitored over longer period of time
if NPH gets into humalog/regular, you won't know to monitor delayed onset, peak and duration
What insulins cannot be mixed? - answer✔✔humalog cannot be mixed with regular
long (Lantus/Levemir) cannot be mixed with anything
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