NURS 5315 UTA Exam 2 UPDATED Exam
Questions and CORRECT Answers
HIV EIA (3rd generation immunoassay) - CORRECT ANSWER- can use urine, saliva, or
serum (most accurate), need to wait until 12 weeks post exposure to see antibodies, >99%
accurate
4th generation immunoassay- "gold standard"
...
HIV EIA (3rd generation immunoassay) - CORRECT ANSWER- can use urine, saliva, or
serum (most accurate), need to wait until 12 weeks post exposure to see antibodies, >99%
accurate
4th generation immunoassay- "gold standard"
measures P24 antigen
can test 10 days post exposure
Mast cell - CORRECT ANSWER- Cellular bags of granules located in loose connective
tisssue close to blood vessels. Activation initiates inflammatory process.
Histamine - CORRECT ANSWER- Causes vasodilation, increases vascular permeability,
increases blood flow to the site of injury- causes erythema and swelling.
Cytokines - CORRECT ANSWER- Soluble factors that contribute to the regulation of innate
or adaptive resistance by affecting other neighboring cells. Can be pro-inflammatory or anti-
inflammatory. Can react quickly or be more delayed.
Leukotrines - CORRECT ANSWER- Released when mast cells degranulate, prolong the
inflammatory process. Cause vasodilation, attract neutrophils, monocytes, and
eosinophils.target of inhibition for singular.
Prostaglandins - CORRECT ANSWER- Released when mast cells degranulate, are produced
by the arachidonic pathway. Cause vasodilation, platelet aggregation at site of injury, pain,
and fever.
Chemotactic factors - CORRECT ANSWER- Biochemical substance that attracts leukocyte
to the site of inflammation
Neutrophils - CORRECT ANSWER- Predominant leukocyte at work during the early stages
of acute inflammation
, Monocytes - CORRECT ANSWER- Become macrophages when entering the tissue,
responsible for presenting antigens to the CD4 cell which triggers T-cell immunity and B-cell
immunity.
Releases additional cytokines IL1, IL6, TNF.
Cytokine IL1 function - CORRECT ANSWER- Causes fever, activates phagocytes &
lymphocytes and also increases the release of IL6a
Cytokine IL6 function - CORRECT ANSWER- Stimulates production of acute phase
reactants and promotes growth and stimulation of RBCs
Cytokine TNF function - CORRECT ANSWER- Causes fever, increases synthesis of
proinflammatory proteins by liver, causes muscle wasting, induces thrombosis
Cytokine growth factor function - CORRECT ANSWER- Promotes production and
maturation of neutrophils
Complement - CORRECT ANSWER- Functions include bacterial lysis, vasodilation and
increased vascular permeability, triggers mast cell degranulation, chemotaxis, and
opsonization.
Kinin - CORRECT ANSWER- Converted to bradykinin which is responsible for pain and
chemotaxis, and it increases vascular permeability and vasodilation.
Coagulation cascade - CORRECT ANSWER- Factor XII activates kinin. Function is to form
fibrin mesh to stop bleeding and trap micro organisms.
COX2 - CORRECT ANSWER- Prostaglandin of arachidonic pathway. Responsible for pain,
fever, renal protection, tissue repair, reproduction development.
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