MN 553 Unit 2 Latest Update 2024-2025 Actual
Exam 250 Questions and 100% Verified Correct
Answers Guaranteed A+
____ are drugs that produce receptor stimulation and conformational change every time
they bind - CORRECT ANSWER: Agonists, or full agonists
_____ are second-line drugs for PMDD - CORRECT ANSWER: Tricyclic clomipramine
and benzodiazepine
______ are inactive compounds that rely on metabolism to activate - CORRECT
ANSWER: Prodrugs
Example: L-DOPA (Parkinson's) can pass into brain, enter cells, and be converted to
Dopamine
______ involves drug molecules being metabolized and something is added to the drug
to synthesize a new compound - CORRECT ANSWER: Phase 2 of metabolism, or
"synthetic or conjugation reaction"
______ is absence of menses for 6 months in a girl who has had a period - CORRECT
ANSWER: Secondary amenorrhea
______ is the process of changing one chemical into another, which either produces or
uses energy - CORRECT ANSWER: Metabolism
______ refers to testicular failure, characterized by low testosterone and elevated
gonadotropins - CORRECT ANSWER: Primary hypogonadism
_______ are drugs that bind to receptors but do not stimulate them - CORRECT
ANSWER: Antagonists
,_______ are first-line therapy for premenstrual dysphoric disorder - CORRECT
ANSWER: SSRIs (fluozetine, paroxetine, sertraline
Also, prostaglandins, NSAIDs, birth control
_______ drugs are first-line therapy for ED - CORRECT ANSWER: PDE-5 inhibitors
Sildenafil (Viagra)
Vardenadil (Levitra)
Tadalafil (Cialis)
_______ is the expression of how much drug is needed to produce a biological
response - CORRECT ANSWER: Potency
50mg drug that produces same response as 250mg drug is more potent
_______ refers to a condition in older men characterized by high donadotropins and
normal testosterone levels. Could represent compensation. - CORRECT ANSWER:
Third category of hypogonadism
_______ refers to the point at which amount of drug being absorbed and distributed is
equal to amount being metabolized and excreted (max concentration of drug) -
CORRECT ANSWER: Peak of action
_______ therapy alone can be safe long-term in menopausal women with a uterus -
CORRECT ANSWER: Estrogen
________ are drugs that bind to receptors but stimulate only some of them - CORRECT
ANSWER: Partial agonists
________ involves the movement of ions, amino acids, and glucose back into
circulation back into cells and into the plasma - CORRECT ANSWER: Tubular
reabsorption
, ________ is absence of menses by age 13 or 15 with secondary sex characteristics -
CORRECT ANSWER: Primary amenorrhea
________ is the ability of a drug to produce a maximum effect at any dosage -
CORRECT ANSWER: Efficacy
Morphine is more efficient at treating severe pain than Motrin. Expresses the maximum
effect a drug is able to produce
________ is the continued entry of a drug into the body with levels above minimum
effective concentration - CORRECT ANSWER: Duration of action
_________ involves filtrate moving through nephron, molecules reabsorbed into blood -
CORRECT ANSWER: Passive glomerular filtration
_________ is the correlation of chemical structure with pharmacological activity -
CORRECT ANSWER: Structure-activity relationship (SAR)
_________ is the percentage of a drug that is absorbed and available to reach tissues -
CORRECT ANSWER: Bioavailability
_________ refers to hypothalmic-pituitary failure and is characterized by low
testosterone and normal gonadotropins - CORRECT ANSWER: Secondary
hypogonadism
_________ refers to the time between administration and first sign of drug effect -
CORRECT ANSWER: Onset of action
__________ are large molecules, usually proteins, that interact with and mediate the
action of drugs - CORRECT ANSWER: Receptors
__________ drugs deposit in bone and teeth - CORRECT ANSWER: Tetracyclines
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