Exam (elaborations)
Advanced Pathophysiology Exam 3 Questions and Complete Solutions Graded A+
- Course
- Institution
Advanced Pathophysiology Exam 3 Questions and Complete Solutions Graded A+
[Show more]
Content preview
AdvancedPathophysiology Exam 3
Questions and Complete
Solutions Graded A+
Denning [Date] [Course title]
,CAD Risk Factors: Non-modifiable - Answer: age
genetic disposition
family history
ethnic background
gender
CAD risk factors - Answer: Age >55
male
fam hx
personal hx peripheral vasc/Cerebrovascular disease
smoking
lipid abnorm
DM
HTN
obesity
sedentary
cocaine
estrogen use
dyslipidemia - high LDL, low HDL, high triglycerides
what happens when LDL becomes oxidized - Answer: becomes oxidized when exposed to endothelial
cells and smooth muscle cell
then exposed to macrophages
becomes foam cell
makes up atherosclerotic plaque
what does HDL do - Answer: reverse cholesterol transport
returns excess cholesterol from the tissue to the liver where it binds to hepatic receptors and is
processed or eliminated as bile or converted to cholesterol-containing steroids
,protects LDL from oxidation
explain the relationship of lipoprotiens and diabetes as a risk factor for CAD - Answer: lipoproteins can
be altered by glycation as a result of high glucose levels which causes a greater integration into
macrophages (engulf oxidized LDL) this then accumulates in the arterial wall causing platelet
aggregation and smooth muscle proliferation
android obesity - Answer: excess body fat that is placed predominantly within the abdomen and upper
body, as opposed to the hips and thighs
strongest link with CAD risk r/t insulin resistance, decreased HDL levels, increased blood pressure, and
inflammation
9 P21 - Answer: genetic variant associated with a strong risk for CAD
what is the risk of having an MI in relation to the age that it occurred in a parent - Answer: inverse
relationship
if you have a parent who had an MI at 40 you have a higher risk than someone who's parent had one at
70
Women typically present with CAD symptoms 10 years earlier than men
t/f - Answer: false
lipoprotein (a) and CAD - Answer: nontraditional risk factor
associated with atherosclerosis and thrombosis
genetically derived particle
at risk for premature CAD as well as stroke
elevated high sensitivity c reactive protein and CAD (hs-CRP) - Answer: acute phase reactant or protein
made in liver
indirect measure of atherosclerotic plaque-related inflammation/progression
inflammatory marker
, the more inflammation the more likely to have plaque ruptures
t/f lipoproteins increase risk for a cardiac event, thrombus, and stroke - Answer: true
t/f high numbers of large and puffy LDL particles are associated with increased risk for CAD - Answer:
false
high numbers of small dense LDL
total cholesterol levels - Answer: desirable - <200
Borderline - 200-239
high - >240
LDL levels - Answer: Optimal: <100
Near optimal: 100-129
Borderline high: 130-159
High: 160-189
Very high: >190
Triglycerides levels - Answer: desirable - <150
borderline - 150 - 199
high - 200-499
very high - >500
HDL levels - Answer: low - <40
high - >60
response to injury hypothesis - Answer: Atherosclerosis hypothesis where plaque build up begins with
the endothelial damage
changes in permeability
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller YourExamplug. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $13.49. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
75632 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now