2. Selective serotonin reuptake inhibitors Fluoxetine (Prozac)
(SSRIs) are a class of medications most Sertraline (Zoloft)
commonly prescribed to treat Paroxetine (Paxil)
depression. They are often used as first- Fluvoxamine
line pharma- cotherapy for depression (Luvox) Citalopram
and numerous other psychiatric (Celexa)
disorders due to their safety, efficacy, Escitalopram
and tolerability. (Lexapro)
3. Adverse
Effects Selective Serotonin
diarrhea Reuptake Inhibitors
headache (SSRIs)
weight gain
sexual side effects
4. inhibit 5-HT reuptake
inhibit NE reuptake (‘ energy, focus) Serotonin Norepinephrine
increase DA in prefrontal cortex (‘ cogni- Re- uptake Inhibitors
tion)
(SNRIs)
5. inhibit DA reuptake (‘alertness, motivation) Norepinephrine Dopamine
inhibit NE reuptake (‘energy) Reuptake Inhibitors (NDRI)
9. no known drug interactions escitalopram (Lexapro)
3/8
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