Exam (elaborations)
ONS CHEMOTHERAPY IMMUNOTHERAPY CERTIFICATE
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ONS CHEMOTHERAPY IMMUNOTHERAPY CERTIFICATE
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ONSCHEMOTHERAPY
IMMUNOTHERAPY
CERTIFICATE
Define neoadjuvant therapy - Answers -Treatment is given prior to surgery to shrink the
tumor
Define adjuvant therapy - Answers -Additional cancer treatment given after the primary
treatment to lower the risk that the cancer reoccur
3 subcategories of alkylating agents: - Answers -1. Nitrogen mustards
2. Platinum-based agents (do not possess an alkyl group but still termed alkylating
agents as they work similarly)
3. Nitrosoureas
Common alkylating agents: - Answers -Cyclophosphamide (Cytoxan)
Ifosfamide (Ifex)
Bendamustine (Treanda)
Common platinum-based agents: - Answers -Cisplatin (Platinol)
Carboplatin (Paraplatin)
What is unique about nitrosoureas agents? - Answers -Able to cross the blood-brain
barrier; can be effective in treating some brain tumors
Common nitrosoureas agents: - Answers -Carmustine (BiCNU)
Lomustine (CeeNu)
Streptozocin (Zanosar)
Hypersensitivity can occur with late doses of: - Answers -Carboplatin
, These agents are typically categorized as highly emetogenic: - Answers -1. Alkylating
agents
2. Nitrosoureas
Minimal-risk emetogenic chemo causes CINV less than ___% of the time - Answers -10
Common IV HEC drugs include: - Answers -Carmustine
Cisplatin
Cyclophosphamide
Dacarbazine
Mechlorethamine
Streptozosin
Common IV MEC drugs include: - Answers -Carboplatin
Cytarabine
Daunorubicin
Doxorubicin
Epirubicin
Idarubicin
Ifosfamide
Irinotecan
Oxaliplatin
Common low-potential IV emetogenic chemo drugs include: - Answers -5-FU
Cytarabine
Docetaxel
Etoposide
Gemcitabine
Methotrexate
Mitomycin C
Mitoxantrone
Paclitaxel
Pemetrexed
Common minimal-risk IV emetogenic chemo drugs include: - Answers -Bleomycin
Bevacizumab
Bortezomib
Busulfan
Cetuximab
Fludarabine
Trastuzumab
Vinca alkaloids
The 2 most important neurotransmitters involved in vomiting are: - Answers -1.
Serotonin
2. Substance P
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