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Pharmacotherapy: A Pathophysiologic Approach 10th Edition Dipiro Talbert Yee
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Pharmacotherapy: A Pathophysiologic Approach 10th Edition Dipiro Talbert Yee
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Pharmacotherapy: A Pathophysiologic Approach 10th Edition Dipiro Talbert Yee
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TEST BANK for Pharmacotherapy: A Pathophysiologic Approach, 10th Edition. DiPiro Joseph, Talbert Robert, Yee Gary, Barbara and Posey | Complete Chapters 1-144
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Test Bank For Pharmacotherapy: A PathophysiologicApproach 10th Edition Dipiro Talbert Yee | 9781259587481 |
All Chapters with Answers and Rationals
Hormones from _____ and _______ provide for growth and maintenance of the female reproductive
organs. - ANSWER: Pituitary gland and gonads
What organs are associated with the regulation of female reproductive system? - ANSWER:
Hypothalamus, pituitary gland, ovary
Gonadotropin-releasing hormone (GnRH) is secreted from the.. - ANSWER: Hypothalamus
Follicle stimulating hormone & leutinizing hormone secreted from the.. - ANSWER: Pituitary
FSH & LH act on the ovary to.. - ANSWER: Cause immature ovarian follicles to begin developing
How & when does the process of ovulation occur? - ANSWER: On day 14 of the ovarian cycle, surge of
LH secretion causes one follicle to expel its oocyte
What is the corpus luteum and how is it developed? - ANSWER: a hormone-secreting structure that
develops in an ovary after an ovum has been discharged but degenerates after a few days unless
pregnancy has begun
- developed from the ruptured follicle that remains in the ovary
Estrogen is a generic term for what 3 different hormones? - ANSWER: 1. Estradiol
2. Estrone
3. Estriol
What kind of metabolic effects does estrogen have on non-reproductive tissues? - ANSWER: 1.
maintain low blood cholesterol levels
2. facilitates calcium uptake by bones to help maintain proper bone density
Name a few responsibilities of the combination of estrogen and progesterone. - ANSWER: 1.
promotion of breast development
2. regulation of monthly changes of the uterine cycles
3. uterine endometrium becomes vascular and thickens in preparation for receiving a fertilized egg
What does high progesterone and estrogen levels in the final third uterine cycle do? - ANSWER: -
provides negative feedback to shut off GnRH, FSH, & LH secretion
What happens when FSH & LH is not secreted? - ANSWER: - estrogen and progesterone levels fall,
endometrium is shed, and menstrual bleeding begins
Oral contraceptives are made up of.. - ANSWER: - combination of estrogen and progestin or
- just progestin
What is the most common estrogen used in oral contraceptives? - ANSWER: Ethinyl estradiol
What is the most common progestin used in oral contraceptives? - ANSWER: norethindrone
Describe the drug administration of oral contraceptives (begin date, length of administration, etc) -
ANSWER: - Begin on day 5 of the ovarian cycle
- Continue taking the drug for 21 days
- 7 days is a placebo
, What does the placebo contain and what is the purpose of having a placebo? - ANSWER: - Purpose: to
promote taking the pill on a daily basis
- Some contain iron to replace iron lost from menstrual bleeding
What happens if the daily does is missed? - ANSWER: - Client takes 2 pills the following day it was
missed
- if more than 1 day is missed, client should also take other contraceptives
How do estrogen-progestin oral contraceptives work? - ANSWER: - provides negative feedback to the
pituitary to shut down secretion of FSH and LH
- no FSH and LH means no maturation of the ovarian follicle, thus preventing pregnancy
- reduces likelihood of implantation bc of the less favourable environment to receive an embryo
- agents are also used to prevent dysmenorrhea
What are the 3 types of estrogen-progesterone formulations? - ANSWER: 1. monophasic
2. biphasic
3. triphasic
Which is the most common estrogen-progesterone formulation? Why? - ANSWER: - monophasic
- delivers a constant amount of estrogen & progestin throughout the menstrual cycle
T/F: estrogen and progestin are delivered in constant amounts with biphasic formulations - ANSWER:
False
Estrogen is constant but progestin is not
- progestin is increased toward the end of the menstrual cycle to nourish the uterine lining
What is another word for progestin only oral contraceptives? - ANSWER: minipills
How progestin only contraceptives work? - ANSWER: Produces thick, vicious mucus at the entrance to
the uterus that discourages penetration by the sperm
- also inhibits implantation of the sperm
T/F: Minimills are more effective that estrogen-progestin combinations? - ANSWER: False:
less effective, failure rate of estrogen-progestins are 1-4%
Why use progestin only oral contraceptives? - ANSWER: Because some clients may be at risk side
effects of estrogen
What is Depo-Povera? - ANSWER: - a long-term formulation
- Deep IM injection called medroxyprogesterone acetate
- coverage for 3 months
What is ortho-evra? - ANSWER: -transdermal patch
- contains ethinyl estradiol and norelgestromin
- changed every 7 days for the first 3 weeks then no patch week 4
What is the NovaRing? - ANSWER: - small ring containing estrogen and progestin
- 3 weeks coverage
- removed week 4, new one is inserted during the 1st week of the menstrual cycle
What is Merena? - ANSWER: - polyethylene cylinder
- placed in the uterus to prevent conception over 5 years
- released levonorgestrel
What is seasonale? - ANSWER: - tablet
- contains levongestrel and ethanol estradiol
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