62 year old woman - osteoporosis - a bisphosphonate is prescribed. The expected
i i i i i i i i i i i i
i beneficial effect of the drug is due to which of the following? -Answer= Decreased
i i i i i i i i i i i i i
i Osteoclast Activity i
Cohot Study of elderly women - relative risk ratio for hip fractures among
i i i i i i i i i i i i
i thosewho exercise regularly is 1.2 (95% confidence interval of 1.1 to 1.8). Which of
i i i i i i i i i i i i i i
i the following is the conclusion about the effect of exercise on the risk of hip
i i i i i i i i i i i i i i
i fracture? -Answer= Statistically Significant Overall Increase Risk
i i i i i i
52 year old man goes to ER with chest pain radiating to his jaw while
i i i i i i i i i i i i i i
i shoveling snow. Pulse is 80/min and blood pressure is 130/70. Thei i i i i i i i i i
i mostimmediate treatment mechanism of action? - Answer= Increased
i i i i i i i i
i nitricoxide concentration
i i
24 year old woman - spilled hot grease on her left leg while working at a fast-
i i i i i i i i i i i i i i i i
food restaurant. Exam of leg shows 7cm pink, soft, granular, edematous
i i i i i i i i i i i
i wound.The formation of this tissue was most likely caused by increased activity
i i i i i i i i i i i i
i of which? -Answer= a. Vascular Endothelial Growth Factor VEGF - stimulates
i i i i i i i i i i
i angiogenesiss.
TYPE III Collagen = Blood Vessels - early wound repair
i i i i i i i i i
27 year old man- MVC - skull x-ray shows a linear, nondepressed basal skull
i i i i i i i i i i i i i
i fracture - increased serum osm and decreased urin osm. Following
i i i i i i i i i
i desmopressin urine osm increases. Desmopressin's effect is due to the i i i i i i i i i
i activationof which of the following? -Answer= a. Adenylyl Cyclase
i i i i i i i i i
, Adenylate Cyclase - ATP - CAMP -
ii i i i i i i
-PROTEKINASE A -- Ca v2
i i i i i
A 10 month old boy - 4 day history of fever and cough. He attends day care
i i i i i i i i i i i i i i i i
i center. Chest exam shows intercostal retractions along with bilateral, diffuse
i i i i i i i i i
i wheezes and expiratory rhonchi. The infectious agent most likely has which of
i i i i i i i i i i i
i thefollowing properties? -Answer= Mediation of Cell Entry via a fusion protein
i i i i i i i i i i i
A 17 year old girl in ED - 15 minutes after being stung by a bee. Mild light
i i i i i i i i i i i i i i i i i
i headedness but no difficulty swallowing- Bilateral wheezing - Which is
i i i i i i i i i
i mostappropriate pharmacotherapy for this patient? -Answer= B2- Agonist
i i i i i i i i
14 year old boy - 2 day history of sore throat and fever that peaks in late
i i i i i i i i i i i i i i i i
i afternoon. 1 week of fatigue. He recentaly had sex with one partner. Physical
i i i i i i i i i i i i
i exam show cervical lymphadenopathy and pharyngeal erythema with a
i i i i i i i i
i creamyexudate. DX? -Answer= Infectious Mononucleosis
i i i i i
, 57 year old man - radiation therapy for squamous cell carcinoma of the lung.
i i i i i i i i i i i i i
i Despite therapy, tumor increases in size and he dies 6 months later. The
i i i i i i i i i i i i
i progressive tumor growth is due to a defect in cell cycle arrest in which of i i i i i i i i i i i i i i
i thefollowing phases of cell cycle? -Answer= G1
i i i i i i i
28 year old - lived in sub-Saharan Africa - until he came to the US. Temp of 100.4
i i i i i i i i i i i i i i i i i
- imaging shows bilateral hydroureter and hydronephrosis. Biopsy shows
i i i i i i i i
i markedfibrosis and scattered granulomas. DX? -Answer= Schistosomiasis
i i i i i i i
A couple with a family history of a-thalassemia. Woman has one gene
i i i i i i i i i i i
i deletionand man has two gene deletion. If the two gene is trans - what
i i i i i i i i i i i i i i
i percentage ofoffspring will have a two gene deletion? i i i i i i i i
-Answer= 50% i
previously healthy 40 year brought to emergency department by her husband
i i i i i i i i i i
- 2 day history of fever, lethargy, confusion. PE shows scattered petechiae
i i i i i i i i i i
i andecchymoses over the lower extremities - 3+ polychromasia and 3+
i i i i i i i i i i
i schistocytes and Low platelets Dx? -Answer= Thrombotic Thrombocytopenia i i i i i i i
i Purpura
16 year old boy - is admitted to the ER because of a knife wound to the left
i i i i i i i i i i i i i i i i i
i sideof his chest. An X- ray of the chest shows an air-fluid level in the left
i i i i i i i i i i i i i i i i
i side of thechest, partial collapse of the left lung, and the elevation of the
i i i i i i i i i i i i i i
i stomach bubble. i
The mediastinum is midline. DX? -Answer= Hemopneumpothorax
i i i i i i
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