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Pharmacology NBME Exam with Complete questions and correct answers
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Pharmacology NBME Exam with Complete questions and correct answers
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Pharmacology NBME Exam with Completequestions and correct answers
Acetylcholinesterase inhibitor (AChE inhibitors) effects Correct
Answer it is an indirect muscarinic agonist so it will produce PNS
like control (SLUD-BBAM)
Malathion Correct Answer an organophosphate insecticide that
acts as an acetylcholinesterase inhibitor
Sarin Correct Answer an organophosphate nerve gas that acts as
an acetylcholinesterase inhibitor
Acetylcholinesterase Restorative Correct Answer Pralidoxime-
which is used to treat organophosphate poisoning especially
nerve gasses
Acetylcholinesterase Restorative effect Correct Answer treats
acetylcholinesterase inhibition so it restores SNS like control
(opposite of SLUD-BBAM)
Acetylcholinesterase inhibitors (AChE inhibitors) Correct Answer
Pyridostigmine
Neostigmine
Edrophonium
Donepezil
Rivastigmine
Tacrine
(Malathion)
(Sarin)
First 3 are for Myasthenia gravis (MG) the next 4 are for
Alzheimer's disease
Ganglionic Blockers Correct Answer Mecamylamine
, Hexamethonium
Trimethaphan
Inhibits the enzymatic breakdown of (neuro) transmitter Correct
Answer MAO-inhibitor effect
MAO-Inhibitor Correct Answer Phenelzine (many side effects)
Ganglionic Blocker effects Correct Answer Will induce the system
opposite of tone so if PNS or an organ is dominant at tone a
ganglionic blocker will induce SNS like control
Endogenous Adrenergic Agonists effect Correct Answer Induce
SNS like control (opposite of SLUD-BBAM)
Endogenous Adrenergic Agonists Correct Answer Epinephrine-
activates a, B1 and B2
Norepinephrine- activates a1>a1>B1 can't effect B2
Dopamine- activates D1 but at higher doses acts at B1 then
alphas
Direct-Acting Alpha Agonists effects Correct Answer Effects will
mimic SNS control on different systems based on the type of
receptor the drug works on
Direct-Acting Alpha Agonists Correct Answer Phenylephrine- a1
(vasoconstriction) used as an antihypotension, decongestant and
a hydriatic
Clonidine- a2 (DECREASES SNS outflow from CNS and
decreases NE release) used to treat hypertension***
Direct-Acting Beta Agonists effects Correct Answer Effects will
mimic SNS control on different systems based on the type of
receptor the drug works on
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