G2 checkpoint Correct answer-checks for cell size and DNA replication
M checkpoint Correct answer-Spindle assembly checkpoint. Mitosis will not continue if
chromosomes are not properly aligned.
MPF Correct answer-mitosis promoting factor
cyclins and cyclin-dependent kinases (cdks) Correct answer-two types of regulatory
proteins involved in cell cycle control
How MPF and cyclins and cdks interact Correct answer-MPF provides a chemical signal
that tells the cell to continue past the G2 checkpoint. MPF is made up of cyclin, a protein
encoded by photo-oncogenes, and a kinase which provides energy through phosphorylation for
process necessary for successful mitosis. The cyclin breaks down after the cell passes through
G2 checkpoint (if it stayed available always, cell would be pushed through G2 checkpoint even if
not ready). The kinase does not degrade and instead stays to be reused later on.
cancer Correct answer-any malignant growth or tumor caused by abnormal and
uncontrolled cell division
6 ket mutations:
-unlimited cell growth
-ignore checkpoints
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