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USMLE Step 1 Biostatistics/Epidemiology Exam Prep Questions And Answers ()
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USMLE Step 3: Rheumatology Exam Prep Questions And Answers(202472025)
rheumatoid arthritis diagnosed with at least 4 of the following criteria: - ✔✔morning
stiffness >1 hr, involvement of MCP, PIP; swelling of at least 3 joints; symmetric
involvement; rheumatoid nodules, X-ray abnormalities showing erosions, +
rheumatoid factor or anti-CCP; CRP or ESR
most accurate test for rheumatoid arthritis - ✔✔anti-cyclic citrulinated peptide
felty's syndrome - ✔✔rheumatoid arthritis, splenomegaly, neutropenia
boutonniere deformity - ✔✔flexion of the PIP with hyperextension of the DIP,
associated with rheumatoid arthritis
swan neck deformity - ✔✔extension of the PIP with flexion of the DIP, asso with
rheumatoid arthritis
baker's cyst - ✔✔out pocketing of synovium at the back of the knee, asso with
rheumatoid arthritis
symptoms for rheumatoid arthritis must last at least how long before diagnosis? -
✔✔6 weeks
what kind of anemia is caused by rheumatoid arthritis - ✔✔normocytic,
normochromic anemia
standard of care for rheumatoid arthritis pts - ✔✔NSAIDs + disease modifying anti
rheumatic drug (methotrexate)
, adverse effects of methotrexate - ✔✔BM suppression, pneumonitis, liver disease
if methotrexate fails in RA, what do you do? - ✔✔add anti-TNF agents like
infliximab, adalimumba, etanercept, hydroxychloroquine or sulfasalazine
if treating mild RA with hydroxychloroquine, what must be monitored? - ✔✔regular
eye exam to check for retinopathy
alternative DMARDs - ✔✔rituximab, anakinra, tocilizumab, leflunomide,
abatacept, gold salts
<40 yo male pt with spine stiffness, pain is worse at night and is relieved by leaning
forward; leads to kyphosis and diminished chest expansion, dx? - ✔✔ankylosing
spondylitis
complications of ankylosing spondylitis - ✔✔uveitis, aortitis, restrictive lung
disease
how prevalent is HLA B27 in ankylosing spondylitis - ✔✔only 8% of the general
population
treatment of ankylosing spondylitis - ✔✔NSAIDs, infliximab or adalimumab,
sulfasalazine, do not give steroids bc they do not work
does methotrexate work well on spine and sacroiliac joints? - ✔✔no so don't use it
for ankylosing spondylitis
keratoderma blenorrhagicum - ✔✔skin lesion (looks like psoriasis) characteristic of
reactive arthritis/reiter's syndrome
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