CRO Prep Exam 2 Questions & Answers 2024/2025
skin - ANSWERS- largest organ in body
- 2mm thick by adulthood
- becomes thinner and more susceptible to sun w/ age
- covers approx. 22 sqft; 10-12 lbs; largest organ
skin functions - ANSWERS- protective
- sensory
- regulatory
most risk ...
- upper 20% = dermal papillae; ridges responsible for fingerprints...papillary region
- lower 80% = reticular region
epidermis layers - ANSWERSdeepest to superficial:
basale
, spinosum
granulosum
lucidum
corneum
melanin - ANSWERS- # of melanocytes is same in all races
- released by MSH; more MSH = more melanin, darker skin
skin cancer - ANSWERS- most common form of cancer (2mil cases per year)
- mostly preventable, curable if treated early
- new cases/deaths have climbed steadily past 30 years
- sunscreen mostly used incorrectly
- sun exposure is cumulative
- lag time for 10-30yrs for clinical appearance
- early prevention is important!!!
melanoma - ANSWERS- most dangerous form of skin cancer
- arises from melanocytes in stratum basale
- most common on legs of women, trunk/face of men
- less than 5% of cases
- risk = 1 in 50 for white, 1 in 1000 for AA, 1 in 200 for hispanic
sunscreen - ANSWERS- spf 30 or higer
- apply thickly, 30 min before exposure, every 2-3hrs; should be applied last
- avobenzone, titanium dioxide, zinc oxide
- insect repellant reduces spf
basal cell - ANSWERS- 800k - 900k of skin cancer cases per year; most common type (BCC)
- starts in stratum basale
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