CRO Exam 1 Questions & Answers 2024/2025
Brain gray matter is central/peripheral and white matter is central/peripheral - ANSWERSperipheral central
Spinal cord white matter is central/peripheral and gray matter is central/peripheral - ANSWERSperipheral central
Where does the spinal cord ...
Brain gray matter is central/peripheral and white matter is central/peripheral - ANSWERSperipheral
central
Spinal cord white matter is central/peripheral and gray matter is central/peripheral - ANSWERSperipheral
central
Where does the spinal cord end in adults? - ANSWERSL1
Where does the spinal cord end in newborns - ANSWERSL3-L4
What is the most common adult primary CNS tumor? - ANSWERSMeningioma 30-35%
What is the 2nd most common adult primary CNS tumor? - ANSWERSGBM 20%
What are the advantages of using IMRT over 3DCRT for CNS tumors? - ANSWERSsparing critical
structures
deliver hot spots in center of tumor
When planning for CNS tumors, what imaging modality is fused with the treatment planning CT and
why? - ANSWERSMRI to delineate target volume
When do the late radiation complications from treating brain and spinal chord neoplasms occur? -
ANSWERS6 months to many years
What is the most common primary malignant CNS tumor in adults? - ANSWERSmalignant gliomas
,What is the most common malignant glioma in the brain? - ANSWERSGBM
What are the two most common presentations of malignant gliomas - ANSWERSheadache seizure
Brainstem gliomas are most common in what type of patients, and when does the incidence peak? -
ANSWERSyoung patients
peaks between 4-6 years
What is the most common benign intracranial tumor in adults? - ANSWERSmeningioma
What is the male:female ratio of meningioma? - ANSWERSF:M = 2:1
Age of incidence for meningioma? - ANSWERS6th & 7th decade
From where do acoustic neuromas arise? - ANSWERSSchwann cells
What two hormones are most commonly secreted from pituitary tumors? - ANSWERSProlactin (30%)
GH (25%)
What is the second most common pediatric CNS tumor? - ANSWERSMedulloblastoma
What percentage of patients have CSF spread at the time of diagnosis of medulloblastoma? -
ANSWERS30-40%
What is CSF? - ANSWERScerebrospinal fluid
When simulating a patient for craniospinal irradiation for medulloblastoma, how is the patient
positioned? (using traditional approach)? - ANSWERSprone extend neck head mask
, How do you calculate the collimator angle of the cranial field to match the divergence of the spine field?
- ANSWERSarctan(.5*length of the superior spinal field/SSD)
When creating a treatment plan using craniospinal irradiation for medulloblastoma, how do you
calculate the couch angle of the spinal field to match the diverging cranial fields? -
ANSWERSarctan(.5*length of cranial field/SAD)
Name two alternate delivery methods for craniospinal irradiation and why would they be employed? -
ANSWERSprotons reduce exit dose
tomotherapy avoid need to match fields
What is Brown-Sequard syndrome and what malignancy is associated with? - ANSWERSipsilateral loss of
motor fine touch sens of pain and temp
primary spinal cord tumors
the CNS includes the ________ and ________ but NOT the peripheral nervous system - ANSWERSbrain
spinal cord
the parenchyma of the brain includes the (3) - ANSWERScerebrum
cerebellum
brainstem
The brain's supporting tissues include - ANSWERSoligodendrocytes
astrocytes
ependymal cells
What percentage of CNS mets to vertebral bodies causes cord compression? - ANSWERS20%
Why is radiation a common treatment for CNS tumors? - ANSWERSSurgery may not be possible
Blood brain barrior prevents chemo
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