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Nursing Pharmacology - Second Year Questions And Answers With Verified Solutions Latest Update 2024/2025.

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Nursing Pharmacology - Second Year Questions And Answers With Verified Solutions Latest Update 2024/2025.

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  • August 4, 2024
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  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • Nursing pharmacology
  • Nursing pharmacology
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Nursing Pharmacology - Second Year Questions And
Answers With Verified Solutions Latest Update
2024/2025.
Explain metabolism - ANSWER The combination of chemical reactions in which an organism
builds up or breaks down materials into more water-soluble molecules

Explain excretion - ANSWER Removal of waste products from the body and filtration of blood
through nephrons in the kidneys, waste excreted in urine.

Explain bioavailability - ANSWER The proportion of a drug within the blood plasma
concentration that is available to reach the site of action.

Explain half life - ANSWER The time it takes for half of the blood plasma concentration of a
drug to be excreted

Explain steady state - ANSWER the amount of drug administrated is equal to the amount of
drug eliminated, resulting in a plateau or constant serum drug levels. above the MEC and MTR

Explain MEC - ANSWER Minimum effective concentration. The amount of drug available in
blood plasma that is too low to produce an effect.

Explain MTR - ANSWER Maximum toxic range. The amount of drug available in blood plasma
that is too high producing side effects and minimum effectiveness.

Explain therapeutic range - ANSWER The range of drug concentration that produces desired
therapeutic effects and lowers the possibility of ADR's

Explain antagonist - ANSWER Blocks receptors inhibiting receptor trigger effects.

Explain agonist - ANSWER Binds to receptors triggering a desired effect

Explain Pharmacodynamics - ANSWER How the drug affects the organism

Explain pharmacokinetics - ANSWER How the organism reacts to the drug (absorption,
metabolism, excretion, filtration)

Explain the first pass effect - ANSWER The drug is metabolized in the intestines then, travels
to the liver for further filtration before reaching systemic circulation.

What is naloxone? - ANSWER an opioid antagonist

What is an example of a non-narcotic? - ANSWER Paracetamol

Explain non-narcotics mode of action. - ANSWER Inhibit prostaglandin synthesis and
serotonergic pathways altering pain signal transmission therefore decreasing pain reception

What are 2 examples of an NSAID? - ANSWER Ibuprofen, celecoxib

What are 3 examples of Narcotics? - ANSWER Morphine, Targin, Oxycodone

, Explain mode of action of NSAIDs. - ANSWER Block COX 1 and COX 2 enzymes inhibiting
prostaglandin synthesis altering pain transmission and inflammation

Explain mode of action of Narcotics. - ANSWER Bind to opioid receptors in the GIT and CNS
reducing pain transmission.

List 5 ADR for non-narcotics - ANSWER Nausea

Vomiting

Diarrhoea

Allergic reaction

Hepatotoxicity

List 5 ADR's for Narcotics - ANSWER Nausea

Constipation

Vomiting

Dizziness

Hypotension

Bradycardia

Bradypnoea

List 5 ADR's for NSAIDs - ANSWER Nausea

Dizziness

GIT ulceration/bleeding

Decreased renal function

Dehydration

List 2 adjuvant medications associated with pain management with their pain effect - ANSWER
Diazepam (benzodiazepine) - muscle spasm pain

Lignocaine - Neuropathic pain

What are the 5 rights of medication administration? - ANSWER Right dose

Right person

Right route

Right drug

Right time

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