define agonist - A drug with a high level of affinity and efficacy that binds to a receptor and casues a
specific action.
define contraindiction - a reason not to use a drug in a particular situation, causes undesirable side
effects
define efficacy - the degree to which a drug produces its desired response.
define over the counter drug - a drug that may be purchased without a prescription from a vet
define prescription drug - a drug that must be prescribed by a vet and taken while under the supervision
of a vet
define receptor - a molecule located on a cell that binds with drugs or neurotransmitters to cause an
effect
define therapeutic index - the relationship between a drug's ability to achieve the desired effect
compared to its tendency to produce toxic effects. Expressed as a ration between the LD and the ED.
LD/ED 50% of the time.
define withdrawal time - the amount of time that must elapse between the end of drug therapy and the
elimination of that drug from the patients tissue or products.
define veterinarian client patient relationship - the relationship that must exist between the
veterinarians, hris or her patient and the patient's owner before prescription drugs may be dispensed
List four sources of drugs used in veterinary medicine - animal products, plant products, minerals, and
synthetic products
, what are four components of a drug regimen - includes the dose, the route of administration, the
frequency of administration, and the duration of administration
discuss the conditions that must be met before a valid veterinarian-client-patient relationship can be
shown to exist. - 1. the vet must assume responsibility for making clinical judgements in relation to the
health of the animal. 2. the vet must have recently seen the animal and be acquainted with its care and
3. the vet must be available for follow up care of the animal.
discuss the responsibilities of a veterinary technician in the administration of drug orders. - carry out
orders correctly, read the drug label 3x to ensure that the proper drug is being adminstered and take
care to administer the correct dose by the correct route. be aware of posibble side effects and monitor
patient in a responsible way.
Describe the sequense of events that a drug undergoes from administration to excretion. - a drug is first
absorbed or directly placed into the bloodstream. In the blood, the drug may bind with a plasma protein
or exist in the free state. The circulating blood distributes the drug to the capillary level, where the drug
leaves the circulation and enters the interstitial fluid. The interstitial fluid bathes the cell or bind with
surface receptors. The drug then exits the cell or its surface, moves back to interstitial fluid, reenters
circulation and then is metabolized in the liver and sent to the kidneys for excretion.
List 11 possible routes for administering a drug and discuss the advatages and/or disadvantages of each.
- 1. oral route 2. SQ 3.IM 4. IV 5. IP 6. IA, intraarterial 7. IC, intracardiac 8. IM, intramedullary 9.
Inhalation 10. topical 11. intradermal
List some of the factors that influence drug absorption - 1. method of absorbtion, 2. the ph of the durg
and its ionization status, 3. the absorptive surface area, 4. the blood supply to the area, 5. the solubility
of the drug, 6. the dosage form, 7. the status of the gi tract 8 interactions with other drugs
Most biotransformation of drugs occurs in where? - liver
Must durg excretion occurs via? - kidneys
Drugs usually produce their effects by combining with specific cellular - receptors
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