Exam 3: NSG318 / NSG 318 (Latest Update ) Introduction to Pharmacology Exam | Questions and Verified Answers | 100% Correct | Grade A - GCU Question: anticoagulants Answer: prevent the formation of clots that inhibit the circulation; prophylactic (does not dissolve clots); used for venous and arterial disorders Question: antiplatelets ( antithrombotic ) Answer: prevent platelet aggregation; mainly used prophylactically Question: thrombolytics Answer: clot busters; used to promote fibrinolytic mechanism; converts plasminogen to plasmin and destroys fibrin in blood clot Question: heparin class Answer: anticoagulant Question: heparin uses Answer: prevent thrombosis associated with PE, MI, unstable angina, prosthetic heart valves, DVT, and percutaneous coronary intervention, treat DIC Question: heparin mode of action Answer: inhibits thrombin which prevents conversion of fibrinogen to fibrin Question: heparin routes Answer: IV- for acute thrombosis SQ- prophylactically Question: heparin contraindications Answer: bleeding disorders Question: heparin cautions Answer: peptic ulcer, hepatic or renal disease, hemophilia, disseminated intravascular coagulation (DIC), diverticulitis, head trauma Question: heparin antidote Answer: protamine sulfate Question: heparin drug interactions Answer: increased heparin effects with aspirin, NSAIDs, thrombolytics, antibiotics, SSRIs decreased heparin effects with nitroglycerin. protamine sulfate Question: heparin side effects Answer: itching, chills, injection site reaction, priapism, hematoma Question: heparin adverse/LT reactions Answer: bleeding, anemia, elevated liver enzymes, stroke; LT: hemorrhage, heparin -
induced thrombocytopenia Question: heparin nursing assessment Answer: obtain history of abnormal clotting or health problems, med reconciliation
