Exam (elaborations)
N450- Quiz -1_ Pharmacology (1)
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N450- Quiz -1_ Pharmacology (1)
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N450- Quiz #1: PharmacologyPharmacokinetics - ANS-the study of drug movement throughout the body
Major Process:
Absorption, distribution, metabolism and excretion
Pharmacokinetics:
Absorption - ANS-The primary factor that determines the length of time for a drug to produce its
effect
Pharmacokinetics:
Distribution - ANS-transport of a drug by the bloodstream to its site of action.
Skin, bone and adipose tissue receive a lower blood supply; therefore, it is more difficult to
deliver high concentrations of drugs to those areas
Pharmacokinetics:
Metabolism - ANS-Enzymes (mainly in liver) transform drugs to less active or inactive drug
compounds or to another substance.
Hepatic disease may affect drug metabolism.
Pharmacokinetics:
Excretion - ANS--remove from body
-primary site (renal)
-other ways to excrete (pulmonary, glandular, fecal and biliary)
Plasma Half Life - ANS-the length of time required for the plasma concentration of a medication
to decrease by one-half after administration.
Greater half life --> longer it takes to be excreted
Trough Level - ANS-The lowest concentration of drug reached in the body, usually measured in
a blood sample for therapeutic drug monitoring.
Usually drawn 30 mins before next dose
Peak Level - ANS-The maximum concentration of a drug in the body after administration,
usually measured in a blood sample for therapeutic drug monitoring.
Usually drawn 30 minutes after IV administration and 1-2 hours after PO
Pharmodynamics - ANS-The process by which a medication works on the body.
Efficacy - ANS-magnitude of maximal response that can be produced from a particular drug
The 5 Rights of Medication Administration - ANS-1. Right patient
2. Right drug
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