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NUR 2060 Pharm Exam 1 PP q-s part 1 (1)
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NUR 2060 Pharm Exam 1 PP q-s part 1 (1)
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NUR 2060 Pharm Exam 1 PP q's part 1Define Pharmacology - ANS-The study of drugs and their interactions with living systems. We
focus on what is clinically relevant.
What are:
1. pharmacokinetics?
2. pharmacodynamics?
3. pharmacotherapeutics? - ANS-1. kinetics: how drug moves through the body
2. dynamics: how drug works in the body (mechanism of action)
3. therapeutics: the use of drugs to diagnose, prevent or treat disease. Prevent pregnancy*
All drugs are intended to have some effect on the body. Name 3 possible effects. - ANS-1.
theraputic
2. toxic
3. fatal
What is the ultimate goal of pharmacotherapeutics? - ANS-For the benefits to outweigh the
negatives.
Name the 3 most important properties of an IDEAL drug in order of importance. - ANS-1.
Effectiveness
2. Safety
3. Selectivity
Define drug effectiveness - ANS-Elicits response for which it is given
Define drug safety - ANS-Cannot produce harmful effects even at very high doses.
Is there such a thing as a completely safe drug? - ANS-No because all humans are subject to
drug toxicity levels or ADR's.
Define drug selectivity - ANS-ONLY elicits response for which it is given with NO SIDE
EFFECTS. There is not such thing as this though since all drugs have ADR's.
What do drug safety, selectivity, and predictability have in common? - ANS-None of them are
100% possible. Not every drug is safe all the time, every drug has the potential for ADR's, and
we cannot know with exact certainty how individual patients will respond to each drug.
Paradoxical Effect - ANS-Variation in individual drug response can cause opposite effects from
one patient to another. (teacher used benadryl as an example).
, Key words or terms to associate with the following:
1. Federal Pure Food and Drug Act 1906
2. FDA Food, Drug Cosmetic Act 1938
3. Harris-Kefauver Ammend 1962 - ANS-1. free of adulterants, weak
2. testing on animals
3. thalidomide tragedy
Key words or terms to associate with the following:
1. Controlled Substances Act 1970
2. Drug Regulation & Reform Act 1978 and Prescription Drug User Fee Act 1992
3. Drug Price Competition Act 1984 - ANS-1. 5 schedules
2. Fast Track
3. Bioequivelance of generic drugs
Key words or terms to associate with the following:
1. FDA Modernization Act 1997
2. FDA Amendments Act 2007
3. Family Smoking Prevention and Tobacco Control Act - ANS-1. expand fast track, warnings,
database on experimental, advertise "off label" use
2. drug monitoring AFTER approval
3. 2009
What is the point of drug legislation? - ANS-To protect the consumer
Why is the bioequivelance of drugs need to ensured? - ANS-Binding agents in drugs can vary
from one brand to another. Although that cannot be changed we must be certain that quantity of
active drug is consistent across trade and generic types.
True or False:
Schedules of Controlled Drugs are arranged in order from 1-5 with 1 having the least potential
for abuse. - ANS-False. The smaller the number the greater the risk for abuse.
Form of prescription and abuse risk for:
Schedule II - ANS-written Rx, no refills
high abuse risk, liability risk
Form of prescription and abuse risk for:
Schedule III - ANS-refill 5 times in 6 months
intermediate abuse risk, liability risk
Form of prescription and abuse risk for:
Schedule IIII - ANS-rules similar to III
penalties for illegal possession
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