AALAS: Introduction to Mice Already Rated A+
1. Which statement is TRUE regarding mice used for research? Mice belonging to the genus Mus bred
for use in research are regulated through PHS policy but are NOT covered by the Animal Welfare Act.
2. What is the primary responsibility of IACUCs re...
AALAS: Introduction to Mice Already Rated A+
1. Which statement is TRUE regarding mice used for research? Mice belonging to the genus Mus bred
for use in research are regulated through PHS policy but are NOT covered by the Animal Welfare Act.
2. What is the primary responsibility of IACUCs regarding laboratory animals? They assure that all
personnel are properly trained to perform animal procedures humanely, provide necessary supportive
care during and after procedures, and follow all protocols.
3. What is the purpose of quarantine/acclimation in animal research? To acclimate animals to their new
environment and reduce stress, rather than rushing them into research protocols to save time and
resources.
4. Why do mice require thermal support during anesthesia? Because they lose body heat rapidly under
anesthesia and can become hypothermic if not provided with proper warmth.
5. What is a common method for collecting blood from mice? Cardiac puncture is generally only
permitted as a terminal procedure, whereas other methods like retro-orbital puncture or tail vein
collection may be used for repeated blood sampling.
6. What can decrease animal pain/distress when using the ascites method of obtaining monoclonal
antibody? Reducing the number of abdominal taps performed, not increasing them, would decrease
animal pain/distress.
7. What is the difference between CFA and IFA? CFA contains killed Mycobacterium tuberculosis, making
it a killed vaccine, whereas IFA is an inactivated vaccine that does not contain killed bacteria.
8. What is the preferred method of anesthesia for extended procedures in mice? Gas anesthesia using a
vaporizer is generally the best option for providing extended anesthesia in mice.
9. Where should survival surgery on mice take place? In an animal procedure room within the animal
facility, where there is controlled access, proper equipment, and trained personnel available.
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