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COMSAE – Questions With Complete Answers (Pass!)
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COMSAE – Questions With Complete Answers (Pass!)
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COMSAE – Questions With Complete Answers (Pass!)von hippel lindau Correct Ans - chromosome 3 tumor suppressor gene UB1a
H-hemangioma
A-angioblastoma
R-renal cell carcinoma
P-pheochromocytoma
sturge-weber syndrome Correct Ans - GNAQ gene
unstable capillary webs
portwine stain
leptomeningeal angioma (seizures)
episcleral hemangioma (early glaucoma)
tuberous sclerosis Correct Ans - TSC1: chr. 9--hamartin
TSC2: chr. 16--tuberin
ash leaf spots
cardiac rhabdomyoma
renal angiomyolipoma
shagreen patch
NF1 Correct Ans - chr. 17--neurofibromin (inhibits RAS)
cafe-au-lait spots
lisch nodules
wilms tumor
scoliosis
pheochromocytoma
NF2 Correct Ans - chr. 22--merlin (schwannomin)
bilateral acoustic schwannomas
juvenille cataracts
affects CN5, 7, 8
ependymoma/meningioma
upper motor neurons Correct Ans - brain to spinal cord
spastic/hypertonic/hyperreflexic
disuse atrophy + babinski lower motor neurons Correct Ans - anterior horn to muscle
flaccid paralysis
hypotonia/hyporeflexia
denervation atrophy (quick)
- babinski
fasciculations
posterior columns Correct Ans - discriminative touch (fine, vibration, proprioception)
ipsilateral
lateral spinothalamic tract Correct Ans - *LST: lower segment three* pain and temperature 2-3 segments below contralateral
(lissauer's tract)
corticospinal tract Correct Ans - motor UMN
ipsilateral
LCST-movement of limbs ACST-movements of axial skeleton
brown-sequard syndrome Correct Ans - hemi-transsection of spinal cord
ipsilateral corticospinal and posterior columns
contralateral LST
cortical stroke Correct Ans - ACA - leg
MCA - face
PCA - vision/language
brainstem strokes Correct Ans - midline - motor symptoms
lateral - sensory symptoms
child brain tumors Correct Ans - astrocytoma
medulloblastoma
ependymoma
craniopharyngioma
pinealoma glioblastoma multiforme Correct Ans - "butterfly appearance"
GFAP+
malignant, midline tumor
psuedopalisading cells
oligodendroglioma Correct Ans - chicken wire capillary pattern
"fried egg" cells
calcified tumors
meningioma Correct Ans - benign
psammoma bodies and spindle cells
arachnoid origin
*MENingioma- PSA*
hemangioblastoma Correct Ans - blood vessel origin
EPO-producing
seen in von hippel lindau
pituitary adenoma types Correct Ans - lactotrophs
somatotrophs
non-functional
lactotroph pituitary adenoma Correct Ans - prolactinoma
low FSH levels
galactorrhea, amenorrhea
gynecomastia, low libido
somatrotoph pituitary adenoma Correct Ans - GH
TSH
ACTH
FSH/LH
non-functional pituitary adenoma Correct Ans - headache
bitemporal hemianopia (no peripheral vision)
schwannoma Correct Ans - S- S100+
C- cerebellopontine angle
H- hearing (CN8)
W- winking (CN7)
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